Diana Barratt, MD Concierge Neurologist and Sleep Medicine Physician

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Diana Barratt, MD Concierge Neurologist and Sleep Medicine Physician

Concierge-Style Neurology and Sleep Medicine Practice in Boca Raton, Florida.

08/03/2026

Clinical trials second opinions.

You may already be in a clinical trial for Alzheimer’s disease, but do you have a treating neurologist? Someone should evaluate your hearing, vision, vitamin and nutrient levels, and sleep. Are your blood pressure and lipids being optimally managed? Are you participating in physical, occupational, speech, and cognitive therapy?

Contact my Boca Raton office for a comprehensive evaluation for mild cognitive impairment or dementia. 561-300-4178

07/28/2026

Are you considering participation in an Alzheimer’s Clinical Trial?
Know your options.

Clinical trials are essential for the advancement of the field of medicine. However, you may qualify for one of the new amyloid-targeting therapies that are already FDA-approved and on the market. You may also benefit from an evaluation for micronutrient deficiencies, sleep disorders, and mood disturbances. Memory and cognition are also impacted by diet, exercise, and cognitive retraining.

To explore all of your options, call my Concierge Neurology and Sleep Medicine Practice in Boca Raton to schedule an appointment. 561-300-4178.

07/27/2026

What is the difference between enrolling as a subject in an Alzheimer’s clinical trial versus being a patient in a comprehensive neurology and sleep medicine practice?

The purpose of a clinical trial is to answer a specific research question. Subjects in the clinical trial must meet very strict inclusion criteria. The subjects may be randomized to receive either the active treatment or a placebo. Physicians conducting the clinical trial may be blinded, meaning they are unaware of whether the subjects are receiving an active treatment or a placebo. There is usually strict adherence to the research protocol.

A patient in a comprehensive neurology and sleep medicine practice can receive cutting edge treatment for Alzheimer's disease. A treating neurologist can choose from a number of different available treatments, even using some in combination. If a patient does not seem to be responding to one particular treatment, a treating neurologist can make modifications. In addition, a treating neurologist can employ multi-modal therapy, including correction of micronutrient deficiencies and treatment for mood disturbances. Exercise, diet, cognitive retraining, and sleep health may also be addressed in a comprehensive neurology and sleep medicine practice. All of the above are known to impact memory and cognition and should be considered as part of the overall treatment of mild cognitive impairment and mild dementia.

Call my Concierge Neurology and Sleep Medicine Practice for an appointment. 561-300-4178.

07/26/2026

Do you need to participate in a clinical trial in order to get the best care for Mild Cognitive Impairment or Mild Dementia due to Alzheimer's disease?

No — and here's what you should know.

FDA-approved, disease-modifying medications are ALREADY available and in use. In Alzheimer's disease, a sticky protein fragment called beta-amyloid builds up in the brain. Amyloid-targeted therapies remove amyloid from the brain and slow progression of Alzheimer's disease.

Amyloid-targeted therapies are accessible to patients right now — no trial enrollment required.

To schedule an appointment, call my Concierge Neurology and Sleep Medicine Practice in Boca Raton, Florida. 561-300-4178.

07/20/2026

Currently available amyloid-targeting therapies as of today--July 20, 2026.

• Both of the amyloid-targeting therapies are FDA-approved for mild cognitive impairment and mild dementia due to Alzheimer’s disease.
• Both are disease-modifying therapies—that is—they slow the progression of Alzheimer’s disease.
• Both require a baseline Brain MRI prior to initiating therapy.
• Both require confirmation of the presence of amyloid beta pathology prior to initiating treatment. I do this by using amyloid PET/CT scans that measure amyloid plaque in Centiloids (the unit of measure).

Donanemab is administered intravenously, every 4 weeks. According to the FDA-approval, a physician can consider stopping the treatment when the amyloid plaque levels have normalized on amyloid PET imaging.

Lecanemab is administered either intravenously (every 2 weeks) or subcutaneously (every week). After 18 months, the physician may transition to maintenance dosing with either intravenous dosing every 4 weeks or subcutaneous dosing every week.

How does one choose amongst the above regimens? I individualize treatment based on the needs of the patient.

07/19/2026

The FDA just approved a subcutaneous formulation of anti-amyloid therapy for mild cognitive impairment and mild dementia due to Alzheimer's disease. Prior to this approval, patients received the initiation therapy in an infusion center. Some patients chose infusions every 4 weeks; others chose infusions every 2 weeks. The newest option is starting anti-amyloid therapy at home. This gives patients the freedom to travel.
Anti-amyloid therapies remove amyloid plaque from the brain and slow the course of mild cognitive impairment or mild dementia. Call my Boca Raton, Florida office for an appointment. 561-300-4178.

07/18/2026

What I am holding in my hand is freedom. Freedom to travel for my patients with mild cognitive impairment or mild dementia due to Alzheimer's Disease. Freedom to stay home, instead of going to the infusion center. Or freedom to go to the infusion center and receive the anti-amyloid therapy intravenously. Anti-amyloid therapies remove amyloid plaque from the brain and slow the course of mild cognitive impairment or mild dementia. Call my Boca Raton, Florida office for an appointment. 561-300-4178.

07/16/2026

Breaking News in Alzheimer's Disease! The new anti-amyloid medication has just been approved for initiation therapy in subcutaneous form. That means patients with mild cognitive impairment and mild dementia due to Alzheimer's Disease no longer have to go to an infusion center to start treatment. Patients have choices and can continue to travel and enjoy their lives. Call my Boca Raton, Florida office for an appointment. 561-300-4178.

07/10/2026

An epidural hematoma is an unambigiuous trauma-related intracranial abnormality. Traumatic brain injury can be diagnosed when there is a plausible mechanism of injury resulting in an epidural hematoma. When brain imaging is abnormal, the qualifier mild TBI with neuroimaging evidence of structural intracranial injury may be used.

07/09/2026

A cerebral contusion is an example of an unambigiuous trauma-related intracranial abnormality. Traumatic brain injury can be diagnosed when there is a plausible mechanism of injury resulting in a cerebral contusion. If brain imaging is abnormal, the qualifier mild TBI with neuroimaging evidence of structural intracranial injury may be used.

Address

5550 Glades Road, Suite 515
Boca Raton, FL
33431

Website

http://DianaBarrattMD.com/

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