05/30/2026
“The CTE diagnosis confirms what my intuition felt...”
Warning: This story contains mentions of su***de that may be triggering to some readers.
Ryan O’Donoghue was a devoted husband, father, and advocate whose life was defined by service and resilience. A former Academic All-American captain and safety for Georgetown football, he began playing football at age nine and also wrestled throughout his childhood. After college, he moved to Colorado, where he became an avid hiker, mountain biker, and expert skier. As longtime CEO of First Descents, he dedicated his career to supporting young adults impacted by cancer.
In the final years of his life, Ryan experienced troubling changes. He struggled to find words, became increasingly clumsy, and had difficulty making decisions. His wife, Tara, sensed something was wrong, but answers were hard to find. Although he was diagnosed with depression, Ryan believed there was a deeper cause. As his symptoms worsened, he told nearly a dozen doctors that he felt he was suffering from dementia. His family says Ryan was not taken seriously.
Ryan died by su***de on May 9, 2025. After his death, researchers at the BU CTE Center diagnosed him with stage 3 CTE. By sharing Ryan’s story, Tara hopes to raise awareness of the disease and help other families facing similar struggles.
Read her interview with The Colorado Sun: https://coloradosun.com/2026/05/15/first-descents-ryan-odonoghue-su***de-cte-brain-disease/
Read Tara’s moving essay on life with Ryan, her search for answers, and her mission to raise awareness about CTE.
https://www.lov.yoga/lov-notes/american-dream
Anyone experiencing suicidal ideation should seek the help of mental health professionals. Those who are worried about a friend or a loved one who may be suicidal should know there are resources available to support them. The 988 Lifeline is available 24/7 by phone or text at 988.
If you or a loved one are concerned about symptoms of CTE, reach out to our free HelpLine for help finding doctors, peer support, and other resources. To submit a request, visit ConcussionAndCTE.org/HelpLine.