10/19/2026
Small study but interesting 🧐
A 2025 study investigated whether a single session of resistance training or high-intensity interval training (HIIT) could increase exercise-related signaling proteins called myokines and influence breast cancer cell growth in 32 breast cancer survivors.
𝗧𝗵𝗲 𝗦𝘁𝘂𝗱𝘆
Researchers divided 32 breast cancer survivors into two groups: resistance training and HIIT. Participants completed a single 45-minute exercise session, with blood samples collected before, immediately after, and 30 minutes after exercise.
Researchers then exposed breast cancer cells to serum from the collected blood samples to evaluate changes in cancer cell growth.
𝗞𝗲𝘆 𝗙𝗶𝗻𝗱𝗶𝗻𝗴𝘀
🔹 Blood samples collected after resistance training were associated with a 21% reduction in breast cancer cell growth in laboratory testing immediately after exercise.
🔹 Blood samples collected 30 minutes after HIIT were associated with a 29% reduction in breast cancer cell growth in laboratory testing.
🔹 Both types of exercise increased levels of myokines, including decorin, IL-6, and SPARC, which may play a role in regulating cancer cell growth.
These findings suggest that even a single exercise session may produce biological changes that influence cancer cell growth in laboratory conditions.
𝗟𝗶𝗺𝗶𝘁𝗮𝘁𝗶𝗼𝗻𝘀
🔹 The study included only 32 breast cancer survivors.
🔹 Researchers examined the effects of a single exercise session, not a long-term exercise program.
🔹 Cancer cell growth was measured in a laboratory using one breast cancer cell line, not in patients.
🔹 The study did not evaluate tumor shrinkage, cancer recurrence, or survival outcomes.
𝗧𝗵𝗲 𝗧𝗮𝗸𝗲𝗮𝘄𝗮𝘆
In this study, a single session of resistance training or HIIT increased circulating myokines and was associated with reduced breast cancer cell growth in laboratory testing. While the findings highlight a potential biological mechanism behind the benefits of exercise, larger studies are needed to determine how these effects translate to cancer outcomes in humans.
𝘐𝘯𝘧𝘰𝘳𝘮𝘢𝘵𝘪𝘰𝘯𝘢𝘭 𝘰𝘯𝘭𝘺. 𝘕𝘰𝘵 𝘮𝘦𝘥𝘪𝘤𝘢𝘭 𝘢𝘥𝘷𝘪𝘤𝘦.