Menopause Brain Doctor

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Menopause Brain Doctor Dr. Manna Semby, ND, MSCP, IFMCP

I went through burnout, breast cancer & chemo/radiation induced extreme brain fog right when I hit menopause.

I'm on a mission to save midlife women's brains from decline so they can be confident and fully themselves.

This week, I will be at the Hilton Bayfront for the annual conference of The Menopause Society. This is my first time at...
10/20/2026

This week, I will be at the Hilton Bayfront for the annual conference of The Menopause Society.

This is my first time attending.

How could I not attend considering it's in my backyard.

We finally have traction in women's health.

In the past two weeks the American College of Physicians finally named estrogen the first-line treatment for hot flashes and night sweats.

The ACOG published its first full menopause guideline since 2014, with a strong recommendation for hormone therapy for hot flashes and the sleep problems they cause.

For those of us who have spent years explaining to women that the 2002 headlines did us a huge disservice, that is a big deal.

At the same time, we are still working around the estradiol patch shortage, and women are calling pharmacy after pharmacy to fill a prescription their doctor finally agreed to write. It’s hard to believe it is still going on.

Here are some highlights on what the conference is about.

The question I most want answered is about breast cancer.

There is a full symposium on the cost of avoiding estrogen, including in breast cancer survivors, and I want to hear whether the thinking for women with estrogen receptor positive cancer is getting more nuanced or are we just saying a blanket NO! for women with hormone positive breast cancer.

Stay tuned.

10/15/2026

I often talk about the importance of managing Homocysteine.

This is an amino acid that is a product of metabolism in our cells.

If its levels are elevated, it means that certain chemical reactions of metabolism are not going to completion and this amino acid is building up.

In higher than certain levels, it can be harmful for heart and brain health.

Now researchers have found that high homocysteine is related to damaged eye vessels which in turn are a predictor of dementia years later.

You see what's happening?

We need to look at your health as a whole - full body and brain health.

Follow me for more on menopause and brain health.

10/14/2026

Two women start hormone therapy, one at 48 and one at 63.

Does it make a difference for their health, for their heart and their brain?

The SWAN study has followed thousands of women through menopause for more than 25 years.

In a new analysis of more than 2,700 women with hot flashes or night sweats, those who started hormones in perimenopause or the early years after menopause had about 22% fewer heart events, and those who started more than ten years after menopause showed no clear heart benefit.

An earlier SWAN analysis found that women who started before their final period scored higher on thinking tests, while women who started after it did worse.

These are observational studies, so they show a pattern that still needs a trial to confirm, and that pattern keeps pointing the same way. When you start matters.

If you're in the menopausal transition now, have the conversation now rather than waiting until symptoms are unbearable.

If you're past that point, it does not mean that hormones can no longer benefit you.

That is a conversation worth having with your doctor.

Follow me for more on hormones and the brain.

My recent conversation with the Sweaty Pillow on menopause and brain health.
10/14/2026

My recent conversation with the Sweaty Pillow on menopause and brain health.

10/13/2026

How old were you when your periods stopped?

It's one of the first questions I ask, and here's why. Your age at menopause may say something about your brain.

A study published this fall in JAMA Network Open followed 2,603 older women for up to 18 years, with memory tests every year and brain scans for some of them.

Women whose natural menopause came earlier had faster memory decline and developed Alzheimer's earlier.

Reaching menopause ten years earlier went with about 1.8 fewer years free of Alzheimer's.

This is an association, and it doesn't predict your future, but it tells me where to pay attention.

If your menopause came early, tell every doctor you see, and start working on the things you can change sooner: blood pressure, blood sugar and sleep.

Follow me for more on menopause and the brain.

10/12/2026

Men and women with the same blood pressure and the same blood sugar may show a different effect on the brain.

That's what a study of more than 17,000 adults from UC San Diego suggests.

The researchers looked at 13 risk factors for dementia in people over 40 and how each one related to thinking scores.

High blood pressure, diabetes and hearing loss were tied to bigger drops in thinking scores in women than in men, and in women in their 50s and 60s, extra weight was too.

It's an observational study, so it can't prove cause, but every one of these is something you can work on.

What can you do today?

Know your blood pressure and your blood sugar, and get your hearing tested.

If you live in California or Colorado and want someone to look at all of this together, my Health Blueprint is where we begin.

The link is in the bio.

10/12/2026

Here is a vindication for all of us.

This week, one of the biggest doctors' groups in the country finally put your symptoms and what can really make a difference to the quality of your life and overall health, first.

On October 5, the American College of Physicians, the group that writes guidelines for internal medicine doctors, named hormone therapy the first treatment for hot flashes and night sweats, in perimenopause and after menopause.

For more than twenty years, so many women were told hormones were too risky and that they should just get through it.

I have sat with women who lost their sleep, their focus and their confidence because no one offered them a real option.

If you now talk to your doctor about hot flashes or night sweats that are wrecking your sleep or your work, hormone therapy will be the first recommendation.

You no longer have to tough it out.

You can have a real conversation with your doctor that considers your own symptoms and your own history.

Follow me for what the research says about hormones and the brain.

10/10/2026

If your mother had dementia, you may ask yourself: am I next?

About six in ten women who sign up for my masterclasses tell me dementia runs in their family, so I know how heavy that question is.

A family history increases your risk, but it doesn't conclusively decide what happens to you. The brain changes that lead to Alzheimer's begin years, even decades, before a diagnosis.

That can sound frightening, but I see it as time: time to measure what is driving your own risk and work on it.

That means looking at your blood pressure, blood sugar, sleep, hormones and inflammation, and your ApoE status if you want to know it.

These are things we can measure today and change.

If you live in California or Colorado and want to start, my Health Blueprint is where we begin.

The link is in the comments. And tell me, does dementia run in your family?

10/09/2026

Do you know about FSH, follicle stimulating hormone?

I've been seeing high FSH for a long time, but lately I'm seeing numbers higher than ever before.

Recently, two women in their sixties came to me with an FSH above 130. Both had thinning bones, both still had hot flashes, and no one had said a word about the number.

FSH is the signal your brain sends to your ovaries, and after menopause it climbs because the ovaries have stopped answering. Once menopause is confirmed, it often isn't checked again.

Data is showing that high FSH goes with faster bone loss, and early research, much of it in mice, suggests it matters for the brain too.

So I look at it.

Ask for your number, and ask what it might mean for your bones and your brain.

If you live in California or Colorado and want someone to look at the whole picture, my Health Blueprint is where we start.

The link is in bio.

10/02/2026

Early cognitive decline is not the same as mild Alzheimer's, and the difference matters.

Forgetting names, losing words or feeling slower than you used to is a change in how your brain is working, not a diagnosis.

Even when testing shows mild cognitive impairment, the cause is often something other than Alzheimer's: poor sleep, hormonal shifts, thyroid problems, low B12, medications, depression or inflammation.

Many of those can be treated, and some people with mild cognitive impairment return to normal.

This is the stage when the brain still has the most plasticity, the ability to build new connections and strengthen the ones it has.

That is why it is the best time to act.

Take the first step here.

https://arunamed,com/health-blueprint

Address

5938 Priestly Drive, Suite 103
Carlsbad, CA
92009

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Wednesday 9am - 5pm
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