A Major Difference, Inc.

A Major Difference, Inc. A Major Difference is the manufacturer and worldwide distributor of the IonCleanse® ionic foot bath.
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Major Difference provides IonCleanse products in Centennial, CO

09/04/2026

The color change gets a lot of attention.

And for good reason! As users can and do detox into the tub.

But one thing going on that isn’t as visible is the stimulation of the parasympathetic response in the body, also known as “rest and digest.”

This nervous system state is where repair happens in the body, and that includes necessary mechanisms like detox.

So not only do you detox into the IonCleanse tub, but you will also continue to detox at an accelerated rate for up to five days *after* your session.

This is why we often refer to the filtered current introduced by our medical grade power supply as the “secret ingredient.” No, it’s not a secret. But it doesn’t seem to get as much attention as the color change, even if it’s a big part of the benefit to this technology.

Skepticism doesn’t scare us. In fact, all of your questions are welcome here. A lot of our biggest believers started out...
08/31/2026

Skepticism doesn’t scare us. In fact, all of your questions are welcome here. A lot of our biggest believers started out as skeptics, so you are in good company.

What do you want to know about detoxing with the IonCleanse? Let us set the record straight.

08/27/2026

The Pay-Per-Cleanse program is a rent-to-own program. Once the user has paid off their machine, the rental unit will be shipped back to us, and they will receive a brand new IonCleanse. It’s a great way to get a device into your home with lower upfront costs. Here, Charles Zeitler runs us through the pro’s and con’s of our PPC program.

Interested in doing the PPC program? Comment below, and we’ll send you a link to sign up.

We don’t want to feel tired. We don’t want to feel pain. We don’t want to feel less than our best. It’s natural and oh-s...
08/25/2026

We don’t want to feel tired. We don’t want to feel pain. We don’t want to feel less than our best.

It’s natural and oh-so-human to want to feel only the good feelings.

But fatigue, pain, irritation, anxiety… these are all messages from the body, too. They aren’t necessarily ‘bad,’ even though they can cause incredible discomfort.

The more we can tune in to what our body is telling us, the less it will have to scream. What is your body asking for today?

08/24/2026

Detoxing the planet two feet at a time since 2002. 👣 The IonCleanse by AMD is a strong and yet gentle full-body detox that works by ionizing the water, splitting it into negative and positive ions.

There are more fun facts where these came from! What questions do you have for us?

If you’ve placed an order with us in the last two years, there’s a strong chance you have points waiting to be used on y...
08/19/2026

If you’ve placed an order with us in the last two years, there’s a strong chance you have points waiting to be used on your account! Here are all of the details about our rewards program so your points don’t go to waste.

08/18/2026

The color change that happens during an IonCleanse by AMD session is truly mesmerizing. 24 years in, and we’re still learning a lot about color change.

The most recent research shows that a IonCleanse by AMD use increases the body’s ability to detox for days after the session. In other words, there’s a lot more going on here than what we can see in the water.

We’d love to hear your stories about color change below. Or if you have any questions, drop them in a comment, and we’ll be in touch.

Everything is connected.The health of the soil shapes the health of the plants. The plants shape the animals. And all of...
08/11/2026

Everything is connected.

The health of the soil shapes the health of the plants. The plants shape the animals. And all of it eventually reaches us.

Glyphosate is one of the clearest examples. Traces of it show up in food and drink products across the board, and it can remain in soil for years after application. What we do to the ground beneath us does not stay there.

Awareness is the first step. Supporting your body is the next one.

Read more about how the IonCleanse can help detox glyphosate on our website, linked in our profile.

08/07/2026

The IonCleanse helps users detox at an accelerated rate for up to 5 days after the cleanse. Dr. Debbie Norman walks us through one of the studies that explains how we know the detox effect keeps going long after your session.

It’s not too late for Christmas in July. 😉 The IonCleanse by AMD is the world’s most effective full-body detox, and it a...
07/28/2026

It’s not too late for Christmas in July. 😉

The IonCleanse by AMD is the world’s most effective full-body detox, and it achieves this all while being non-invasive. Try the system for yourself with our 60-day money-back guarantee. If you’re not pleased with your results, send it back for a full refund.

Address

7318 S Revere Pkwy #B7
Centennial, CO
80112

Opening Hours

Monday 8am - 5pm
Tuesday 8am - 5pm
Wednesday 8am - 5pm
Thursday 8am - 5pm
Friday 8am - 5pm

Telephone

+13037550112

Website

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