JAMA Psychiatry

05/24/2026

Normative modeling of morphometric similarity networks in identified three distinct biotypes with unique clinical-neural profiles, supporting more neurobiologically informed stratification for ADHD management.

https://ja.ma/4wJLgsD

05/23/2026

Among male patients with in an inpatient setting, a randomized clinical trial indicates that integrating as adjuvant therapy alongside standard treatment accelerated opioid withdrawal stabilization, reducing median time to minimal withdrawal symptoms from 9 to 5 days.

Improvements in heart rate variability, anxiety, sleep latency, and pain were observed, suggesting a measurable effect on autonomic regulation.

Learn more about the clinical implications of these findings in this interview with Hemant Bhargav, MD, PhD, and JAMA Psychiatry Web Editor John Torous, MD.

https://ja.ma/43mVq4X

05/23/2026

Reduced is observed in patients with , current and remitted vs healthy controls, reflecting persistent motor and motivational dysfunction across diagnostic groups. https://ja.ma/4nJf7xp

05/22/2026

Military sexual trauma prevalence remains high among US veterans, especially females, and is associated with increased risk for suicidal thoughts and behaviors. https://ja.ma/4dqJrcG

05/22/2026

Individual variability in synaptic gene expression and synapse density in induced pluripotent stem cell–derived neurons predicted macro-scale alterations in gray matter volume and gamma-band activity in patients with . https://ja.ma/42Kpwzf

05/21/2026

Systemic interleukin-6 inhibition demonstrated treatment-sensitive outcomes and clinically meaningful effect sizes in patients with difficult-to-treat and low-grade . https://ja.ma/4tMRENc

05/21/2026

An umbrella review found interventions yield moderate improvements in tension, fatigue, confusion, and affect, but evidence for climate-related psychosocial interventions remains limited.

This umbrella review and meta-analysis evaluates associations of climate-related and nature-based mental health interventions with mental health outcomes.

05/20/2026

Family genetic risk scores across 18 psychiatric disorders indicated six correlated factors: psychotic, externalizing, anxiety, neurodevelopmental, mood, and eating disorders. https://ja.ma/4digOhJ

05/20/2026

Among adults with severe mental illness, integrating into psychiatric care improves psychiatric symptoms, cognitive health, and cardiometabolic outcomes, supporting longer life expectancy. https://ja.ma/4wFCxYu

05/19/2026

Health plan disenrollment after initiating medications for was associated with increased all-cause and overdose mortality compared with remaining enrolled. https://ja.ma/4v1l638

05/18/2026

Normative modeling of morphometric similarity networks in identified three distinct biotypes with unique clinical-neural profiles, supporting more neurobiologically informed stratification for ADHD management. https://ja.ma/4dtXpJj