08/08/2024
Does Akkermansia increase GLP-1? Can it reduce your appetite?
My answer is NO...Let’s break it down…
Akkermansia is an important probiotic in the health of the gut lining. It has been shown to be low in individuals with metabolic issues. Increasing it can improve some of these issues, such as insulin resistance. The research supports this.
But…there is not enough supportive research to say that it increases GLP-1. Thus far, there is a single study looking at the hypothesis that Akkermansia can increase endogenous GLP-1 levels. And it was done in 🐭. That’s not enough evidence for me to jump on the bandwagon or recommend my patients jump on the bandwagon of taking an overpriced probiotic that is only available from one company.
Lesson 🤓: Don’t be fooled by marketing. Do your research.
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PMID: 35874661
PMID: 33820962