08/31/2026
Losing weight and improving your body composition are not the same thing.
If you've lost significant weight with a GLP-1 medication, an important question is:
How much of that weight was fat—and how much was lean muscle?
In this video, Dr. Joel Cherdack explains what he calls the Body Composition Stack: a comprehensive approach designed around reducing excess body fat while helping preserve the muscle that becomes increasingly important as we age.
Topics include:
✅ Why preserving muscle matters during weight loss
✅ GLP-1 medications and the importance of monitoring lean mass
✅ Growth hormone secretagogue peptides such as Ipamorelin, CJC-1295, and Tesamorelin
✅ MOTS-c and emerging research into mitochondrial and metabolic health
✅ Why resistance training is essential for muscle preservation
✅ The importance of adequate protein, sleep, and recovery
The goal shouldn't simply be to weigh less.
The goal is less excess body fat, preserved muscle, better metabolic health, and a stronger, more functional body as you age.
Peptide therapies should be individualized and medically supervised. Some peptide applications discussed in longevity and performance medicine remain investigational or are used off-label.
Learn more:
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