06/11/2026
Phosphatidylserine (PS) is a phospholipid concentrated in neuronal membranes, where it plays a key role in HPA‑axis regulation, synaptic signaling, and cognitive processing. Supplementation has been shown to attenuate ACTH and cortisol responses to stress, support membrane‑dependent neurotransmission, and improve attention and memory performance, which may reduce stress‑related behaviors such as nighttime jaw clenching and teeth grinding. This means support for anyone stuck in fight or flight.