MedGenyx, PLLC

06/23/2026

Have you or someone you love been prescribed azathioprine, mercaptopurine, or thioguanine?

These medications, used for Crohn's disease, ulcerative colitis, rheumatoid arthritis, organ transplant rejection, and certain childhood leukemias, can be very effective. But for some people, there is a serious risk of bone marrow suppression based on how their bodies process them genetically.

CPIC, the gold-standard organization for pharmacogenomics guidelines, just released a major update: the 2025 Thiopurine Dosing Guideline. The big news is that patients who carry genetic variants in both TPMT and NUDT15 (two enzymes that break down these medications) now have their own specific dosing guidance for the first time.

Previously, people in that "double intermediate" category didn't have a clear recommendation. Now they do: a greater dose reduction than either gene alone would suggest, which may help protect against serious side effects.

The update also provides clearer, drug-by-drug guidance, so prescribers can make more precise decisions based on both the patient's genetics and their specific condition.

At MedGenyx, we specialize in exactly this kind of personalized medication guidance. A simple genetic test could reveal whether standard doses of these medications pose a risk before any harm occurs.

Curious whether this applies to you or a family member?

Book a Free Discovery Call → https://medgenyx.practicebetter.io/ #/62f1a6008b0c27addd549003/bookings?r=6338a1f6c97de21f47f64e47

06/17/2026

Some of the most commonly prescribed medications already have published pharmacogenomic guidelines.

That means there is established science connecting genetic variation to how those drugs work and who they work best for. Testing can determine whether a medication is likely a good fit or whether an alternative may serve the patient better.

The guidelines exist. Now it's about using them.

06/12/2026

Happy Healthcare Professionals Week to every doctor, nurse, pharmacist, therapist, and care team member out there. 💙

Behind every prescription is a professional who spent years learning how to help people. And behind every adverse drug reaction is a story we wish we could have caught earlier.

At MedGenyx, we believe that pharmacogenomics, understanding how your unique DNA affects how your body processes medications, can be one of the most powerful tools in a healthcare professional's toolkit.

When providers have access to a patient's genetic medication profile, they can:
• Anticipate which medications may work better or cause side effects
• Adjust doses before problems arise
• Replace trial-and-error with a more informed starting point

This week, we celebrate the professionals who make personalized care possible, nd we're here to help them go even further.

Know a healthcare provider who might benefit from learning more? Share this with them.

Book a Free Discovery Call → https://medgenyx.practicebetter.io/ #/62f1a6008b0c27addd549003/bookings?r=6338a1f6c97de21f47f64e47

06/11/2026

What if your doctor could choose a medication already matched to your biology?

Genetic insights are changing how treatments are selected, and we are moving away from trial-and-error toward options that may be more effective and better tolerated from the start.

That's not the future of medicine. It's happening now.

05/29/2026

Did you know your DNA may affect how well your anti-nausea medication works?

CPIC — the organization that sets the gold standard for pharmacogenomics guidelines — just released a major 2026 update. It now covers ALL of the most commonly prescribed anti-nausea medications, including ondansetron (Zofran), granisetron, and palonosetron.

Here's the simple version: Some people are "Ultrarapid Metabolizers" of a liver enzyme called CYP2D6. That means their body may process certain anti-nausea medications so quickly that the drug doesn't have time to work — which can lead to breakthrough nausea, especially during chemotherapy or after surgery.

The good news? There are alternative medications that work differently — and a genetic test can help identify which option may be the better fit for you.

This update now also includes children, which is a meaningful step toward more personalized care for younger patients going through difficult treatments.

At MedGenyx, we specialize in exactly this kind of personalized medication guidance. We help you and your care team understand what your DNA may mean for how your body handles the medications you've been prescribed.

Curious whether pharmacogenomics could make a difference for you or someone you love?

Book a Free Discovery Call → https://medgenyx.practicebetter.io/ #/62f1a6008b0c27addd549003/bookings?r=6338a1f6c97de21f47f64e47

This update now also includes children, a meaningful step toward more personalized care for younger patients undergoing difficult treatments.

05/27/2026

If you've ever experienced an unexpected or severe side effect, your genetic profile may explain why. And more importantly, it may help prevent the same thing from happening again.

Genetic data doesn't just look back. It protects what's ahead.

05/20/2026

Happy Global PGx Day! 🌍

Did you know your DNA can influence how your body responds to dozens of common medications, from antidepressants to blood thinners to pain relievers?

Pharmacogenomics (PGx) testing removes the guesswork from prescribing. One simple cheek swab may help your care team make smarter, safer medication choices personalized to you.

MedGenyx is proud to join the global movement making precision prescribing the standard, not the exception. Learn more and book a Free Discovery Call at the link in Bio.

05/13/2026

Tried medication after medication with no relief? Your genes may hold the answer.

For patients who have cycled through multiple treatments without success, pharmacogenomic testing can be a turning point. We help identify why past options didn't work and what might actually be a better fit.

No one should have to keep starting over.

05/08/2026

A cotton swab. Thirty seconds. A lifetime of better prescribing decisions.

Your DNA holds clues about how your body processes medications, and a simple cheek swab can unlock them.

Pharmacogenomic testing doesn't just add information; it adds precision.

Because the right medication at the right dose shouldn't be a guessing game.

05/06/2026

“Genotype-Guided Antidepressants Could Have Long-Term Benefits.”

A clinical trial suggests that genotype-guided prescribing of selective serotonin reuptake inhibitors could have long-term clinical benefits.