The Neurogenesis Project

The Neurogenesis Project Optimize and Enhance your Brain Function and Cognitive Capacity for a healthier, happier, and more productive life. Contact us for a consultation.

Precision-based, personalized, and proactive Brain Health care.

What if the most promising new tool against opioid relapse turned out to be a drug your pharmacy has carried for decades...
06/03/2026

What if the most promising new tool against opioid relapse turned out to be a drug your pharmacy has carried for decades?

A 2026 University of Iowa study showed that acetazolamide, an old glaucoma medication, reverses the synaptic rewiring in the reward center that current addiction medications do not touch. A single dose was enough to reduce drug-seeking in animal models after long abstinence.

Dr. Drew Edwards breaks down what the finding means for people in recovery and the families supporting them: https://neurogenesisproject.com/blog/acetazolamide-opioid-relapse-brain-rewiring

If you or someone you love has been told that staying clean is just a matter of motivation, what would it change if you knew the science says otherwise?

Has your doctor told you your POTS or chronic fatigue is "just anxiety"?A new peer-reviewed review from Stanford and the...
06/02/2026

Has your doctor told you your POTS or chronic fatigue is "just anxiety"?

A new peer-reviewed review from Stanford and the University of Buffalo analyzed the evidence across POTS, ME/CFS, and Long COVID and concluded these are neuroimmune disorders with measurable brainstem inflammation, immune dysregulation, and autonomic failure.

7-Tesla MRI shows structural damage at the dorsolateral medulla. PET scans reveal activated microglia. Blood panels show autoantibodies attacking the autonomic nervous system.

This changes everything about how these conditions should be diagnosed and treated.

Read Dr. Orr's full analysis: https://neurogenesisproject.com/blog/pots-mecfs-neuroimmune-diseases

Have you been told your symptoms are "in your head"? What was your experience getting a diagnosis?

What if mania is not a chemical imbalance, but a metabolic and inflammatory failure of the brain's regulatory governor?I...
06/01/2026

What if mania is not a chemical imbalance, but a metabolic and inflammatory failure of the brain's regulatory governor?

In our clinic, we treat acute bipolar crises with IV neuronutrients, NAD+, glutathione, and stem cell-derived exosomes — restoring the substrate that conventional psychiatric medications are trying to act on. Patients who would have been hospitalized and sedated for days or weeks instead recover within an hour or two. Depression responds in days, sometimes hours, not weeks.

https://neurogenesisproject.com/blog/bipolar-inflammation-iv-treatment-mania-depression

What would change if your psychiatrist treated the brain's biology, not just its symptoms?

What if menopause isn't "normal aging" at all?New research from UCSF shows the o***y is directly wired into the nervous ...
05/31/2026

What if menopause isn't "normal aging" at all?

New research from UCSF shows the o***y is directly wired into the nervous system, and when it goes offline at menopause, the brain loses the hormonal signals that maintain gray matter volume, glucose metabolism, and synaptic plasticity in the frontal and temporal lobes.

Dr. Sean Orr breaks down the neuroscience of menopause as a treatable neurodegenerative condition, and what women in their 40s and 50s should be asking their doctors.

Read the full article: https://www.neurogenesisproject.com/blog/menopause-neurodegenerative-disease-treatable

Have you or someone you know experienced cognitive changes during menopause that were dismissed as "normal"?

What if Alzheimer's pathology was already in your brain at 61, and your normal cognitive screen missed it entirely?That'...
05/30/2026

What if Alzheimer's pathology was already in your brain at 61, and your normal cognitive screen missed it entirely?

That's what a new Lancet study from UCSF just found in 6% of dementia-free middle-age adults. Five years later, those adults had nearly four times the risk of rapid decline in processing speed.

Dr. Sean Orr breaks down what the CARDIA study means for how we think about brain health in midlife: https://www.neurogenesisproject.com/blog/lancet-alzheimers-pathology-midlife-brains

Have you noticed subtle slowing in your 50s or 60s — finding the right word, rereading paragraphs, slower reaction time?

What if some of the patients we call "idiopathic" actually have a treatable cause of cognitive impairment that nobody ha...
05/29/2026

What if some of the patients we call "idiopathic" actually have a treatable cause of cognitive impairment that nobody has bothered to test for?

Folate receptor alpha autoantibodies block folate transport into the brain. A blood test finds them. Leucovorin bypasses the block. The evidence is strongest in autism, but the same biology may apply across the cognitive spectrum, from infantile regression to adult dementia.

Dr. Sean Orr breaks down the science, including the choroid plexus mechanism, in our latest piece.

https://neurogenesisproject.com/blog/folate-receptor-antibodies-treatable-cognitive-impairment

Have you ever had this antibody tested?

What does alcohol recovery actually look like inside the brain?A new EEG study out of the University of Manchester separ...
05/29/2026

What does alcohol recovery actually look like inside the brain?

A new EEG study out of the University of Manchester separated two reward-feedback signals in 46 adults. One was blunted in everyone with a history of alcohol dependence and never recovered. It looks like a brain trait, not damage from drinking. The other rebuilt itself slowly, over years of sobriety. Twenty-eight days is not the timeline. Twenty-eight months is closer.

Dr. Drew Edwards walks through what this means for anyone in recovery, and for the families and clinicians trying to help.

https://www.neurogenesisproject.com/blog/eeg-alcohol-recovery-brain-signals

Have you watched someone you love wait years for "normal" to come back after they got sober? What helped most during the in-between?

What if your "chronic back pain" is actually a brain clearance problem?Arachnoiditis inflames the same membrane that abs...
05/24/2026

What if your "chronic back pain" is actually a brain clearance problem?

Arachnoiditis inflames the same membrane that absorbs your cerebrospinal fluid. When it scars, the downstream picture often looks indistinguishable from normal pressure hydrocephalus: wider gait, urinary urgency, and cognitive slowing that nobody connects back to the spine.

Dr. Sean Orr breaks down why arachnoiditis is a CSF clearance disease, not a pain syndrome, and what a real workup should include.

https://www.neurogenesisproject.com/blog/arachnoiditis-csf-clearance-disease

Has anyone in your family been told they have arachnoiditis or NPH and felt the workup was incomplete?

What if the patient who keeps relapsing on alcohol has been on the wrong medication for the wrong target the entire time...
05/20/2026

What if the patient who keeps relapsing on alcohol has been on the wrong medication for the wrong target the entire time?

A new systematic review at the American Society of Addiction Medicine 2026 meeting found that ketamine works on both depression and alcohol use disorder at the same time, through a glutamate pathway SSRIs do not touch. For the thirty to forty percent of patients with AUD who also have major depression, that is a different conversation.

Dr. Drew Edwards on what this means for patients who have been told their depression has to wait until they get sober:

https://www.neurogenesisproject.com/blog/ketamine-comorbid-depression-alcohol-use-disorder

Have you or someone you love been bounced between an addiction counselor and a psychiatrist with neither one fully taking the case?

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6320 St. Augustine Road, Suite 7B
Jacksonville, FL
32217

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https://patreon.com/TheNeurogenesisProject

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