Jonas Kuehne MD

Jonas Kuehne MD Preventive Health MD
đź’Ş Weight Loss
🥦 Nutrition
⚕️Disease Prevention

09/03/2026

If you’re dealing with hair thinning or hair loss, topical finasteride + minoxidil is one combination worth knowing about.

Finasteride works by inhibiting 5-alpha reductase, which reduces DHT. DHT plays a major role in androgenetic alopecia, also known as male pattern hair loss, because it contributes to progressive hair follicle miniaturization.

Minoxidil works through a different pathway. It supports hair growth and helps prolong the growth phase of the hair cycle.

Why do I like the combination?

You’re addressing hair loss through two different mechanisms at the same time.

Using finasteride topically is also an interesting option for patients concerned about systemic exposure. Topical finasteride still gets absorbed to some degree, but systemic exposure tends to be lower than with oral treatment.

For men experiencing male pattern hair loss, topical finasteride + minoxidil is a treatment worth discussing with your physician.

Different formulations and concentrations are also used for women depending on the individual and the cause of hair loss.

Hair loss treatment is much more effective when you identify what is driving it first.

Save this if you’re researching hair loss treatments, finasteride, minoxidil, DHT, male pattern baldness, thinning hair, or hair regrowth.

08/29/2026

Women with low testosterone have a solution that works. Men do not, and the data is clear on why.

Low testosterone affects both sexes. Decreased libido, bone density loss, muscle loss, persistent fatigue. But the fix is not the same for men and women.

DHEA is produced by your adrenal glands. In women, it’s the primary source of testosterone production. Studies show DHEA supplementation in women increases both total and free testosterone effectively.

In men, the results are disappointing. A portion of that DHEA converts to estrogen instead of testosterone, which means some men end up with more estrogen and no real testosterone gain. The opposite of the intended outcome.

One more important point: a precursor like DHEA is a better approach than taking finished testosterone directly, because exogenous testosterone suppresses your body’s own production. DHEA lets your body do the conversion itself.

This is not medical advice. It’s something to bring to your physician and explore based on your own labs and symptoms.

Comment PROTOCOL below and I’ll send you my full supplement protocol.

08/29/2026

I like potato chips. I avoid seed oils. So I have been paying extra for the ones labeled 100 percent avocado oil.

Turns out I was being lied to.

UC Davis tested 54 processed foods listing avocado oil as the only oil ingredient. 93 percent of the chips failed. Most contained canola, safflower, or soybean oil instead.

The economics explain everything. Real avocado oil runs 4 to 5 dollars per pound. Seed oils cost 50 cents to a dollar fifty. The label premium is real. The oil is not.

This is not a new problem for this research group. A 2020 study found 82 percent of bottled avocado oils were rancid or cut with cheaper oils. The fraud simply moved from the oil aisle into the snack aisle.

Reading labels stopped being enough. When a price gap this wide meets almost no oversight, treat every premium claim as marketing until someone tests it.

Comment FOOD and I will send you my free guide with six powerful health strategies plus the ingredients to avoid while shopping.

08/27/2026

One of the most common questions I get about GHK Copper is this.

Should you apply it to your skin or inject it? 🤔

The answer is not as simple as choosing one over the other.

GHK Copper is a small peptide made of glycine, histidine, lysine, and copper. Because of its size, some of it is absorbed through the skin. Current estimates suggest topical absorption is around 10% to 30%, although we still need better data to know the exact amount.

Topical application makes sense because your target is the skin. GHK Copper has been studied for its role in supporting collagen production and improving skin quality. ✨

Subcutaneous injections provide much higher overall absorption because they bypass the skin barrier. The unanswered question is how much of the injected peptide ultimately reaches the skin where you want it to work.

Based on current evidence and biological theory, combining topical and injectable GHK Copper might provide the greatest benefit. More human studies are needed before we know the answer with confidence.

Comment RESET and I’ll send you my beginner’s guide to peptide therapy. 📩

08/25/2026

Yes. For Jonas, I would make it unmistakably first-person and physician-led, with phrases like “what I see in my patients” and “what I focus on in my practice.”

One of the biggest GLP-1 mistakes I see is assuming you need the maximum dose to get the best results.

In my practice, I’ve had patients stay on the lowest dose of tirzepatide and lose 20+ pounds while maintaining muscle mass and bone density on their DEXA scans.

Some patients need higher doses. Others don’t.

My goal as a physician isn’t to get you to the maximum dose. It’s to find the lowest effective dose that gives you results while protecting what matters.

Because I don’t only look at the number on the scale.

I want my patients to:
• Lose body fat
• Maintain muscle mass
• Protect bone density
• Eat enough protein
• Strength train consistently
• Use the lowest effective GLP-1 dose for their individual response

Losing weight fast means very little to me if a significant part of that weight is muscle.

The goal is better body composition and better long-term health.

Save this if you’re taking or considering a GLP-1, and follow me for more evidence-based guidance on GLP-1 medications, metabolic health, and longevity.

08/19/2026

The hormone panels I see in young patients are consistently lower than they should be. Chemical exposure from plastics is a major contributor, and one source most people never consider is clothing.

Your workout clothes sit directly against your skin while you sweat. Heat and moisture dramatically increase absorption. The higher the synthetic fiber content, the more chemical transfer you get. Tight stretchy leggings made from synthetic material, worn during a sweaty workout, are the worst version of this.

What to do: choose cotton, keep athletic wear looser, and avoid skin-tight synthetics. A small percentage of stretch fiber in mostly cotton clothing is far less concerning than a fully synthetic garment.

Clothing is only one input. Food exposure is likely larger.

Hot liquids in paper cups lined with plastic. Anything heated in plastic containers. Styrofoam takeout. Fast food wrappers, which used forever chemicals until recently, and existing stock stays in circulation until it runs out. Then pesticides, herbicides, microplastics, and nanoplastics, all concentrated in lower quality food.

Choosing organic reduces the load meaningfully.

You will not eliminate these exposures. You can lower the total dose, and dose is what determines the damage.

Which one of these are you willing to change first?

08/18/2026

Want access to the product I personally developed and use daily? Comment “FACELIFTER” and I’ll send you the details.
One of the visible hallmarks of aging is facial muscle loss.

As facial muscles deteriorate, the overlying tissue sags and wrinkles form.

GLP-1 agonists accelerate this process.

These weight loss drugs cause rapid weight loss, but they also trigger muscle loss and connective tissue loss at an accelerated rate. Your face shows it first. Sagging skin, deeper wrinkles, hollowed features.

The problem: GLP-1s don’t discriminate between fat loss and muscle loss. You lose both. Your facial muscles shrink faster than they would naturally, aging your appearance dramatically.
This is the hidden cost of rapid weight loss without proper muscle preservation strategies. People celebrate the number on the scale while their face ages years in months.

I developed a solution for this exact problem. A topical product that supports facial muscle structure and connective tissue integrity.

I use it daily because I understand the importance of maintaining facial volume and elasticity as we age.
Prevention is easier than reversal.

08/11/2026

Roughly 40 million Americans have diabetes, and 95 percent of those cases are type 2. Treatment has improved enough that lifespan for diagnosed patients has increased substantially.

The people I worry about are the ones who have not been diagnosed yet.

They sit right at the border, where no official diagnosis gets made. Visceral fat is accumulating. Inflammation is elevated. Blood sugar runs high. And insulin climbs higher and higher as the body compensates to push sugar into cells that are becoming resistant.

This is where the damage starts, and it includes dementia. When neurons become insulin resistant, glucose cannot enter the cell. The cells starve. Inflammatory markers rise, free radicals form, and that cascade sits at the earliest stage of what eventually becomes dementia.

Hemoglobin A1C catches the problem late. Fasting insulin catches it early, because the body compensates by producing more insulin long before blood sugar looks abnormal on a standard panel.

Ask for a fasting insulin, especially if you are struggling with your weight. Visceral fat gain is the first domino in this entire sequence.

The disease you catch early is the one you still control.

Comment FOOD and I will send you my free guide with six powerful health strategies plus the ingredients to avoid while shopping.

04/30/2026

Most doctors have never heard of Epitalon.

The ones who have aren’t talking about it enough.

Here’s what the research shows and how to use it correctly.

The original Russian studies used epithalamine, a natural pineal gland extract, at doses of 5 to 10 milligrams daily for 10 to 20 days.

Today, most people use synthetic Epitalon, which is more potent and pure.

The recommended dose for synthetic Epitalon is 500 micrograms to 1 milligram daily for 10 to 20 days, twice a year. You run one cycle, wait at least 6 months, then repeat.

Most people do 2 cycles per year.

You are not taking this every day forever.

You use it strategically to reset your telomeres, restore pineal function, boost your immune system, and then step back and let your body stabilize.

That’s what makes this longevity peptide different from anything else in an anti-aging protocol.

Side effects are minimal. Human trials reported very few issues.

Some people noticed mild redness and soreness at the injection site.

Some felt more tired in the evening, which makes sense because Epitalon ramps up melatonin production. Avoid injecting late in the afternoon if you have evening plans.
This is not medical advice.

Always consult your physician before starting any peptide protocol.

Have you tried Epitalon or are you currently running a peptide cycling protocol?

Drop your experience in the comments below.

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