Simon Hill

Hey friends, I'm Simon Hill.
(2)

I am a qualified physiotherapist & nutritionist, the host of the The Proof podcast and author of The Proof is in the Plants 🌱

Connect with me on Instagram and Twitter

10/07/2026

After my retatrutide post, one of thr most common questions I received was “what about muscle?”

Fair question. Up to 40% of the weight lost on these drugs isn’t fat, and that number gets thrown around a lot. But “lean mass” on a scan isn’t the same as muscle. It also includes water, stored carbs, organs, and connective tissue.

The short version: muscle loss on these drugs looks to be in proportion to the amount of weight lost, and muscle quality often improves as fat inside the muscle clears. That doesn’t mean you can ignore it, especially if you’re older, already low in muscle, or planning to come off the drug.

Resistance training and prioritising protein are your best insurance.

Swipe through for the evidence, including the latest on retatrutide. If you want to go deeper, Dr Nicola Guess and I unpack this in EP 432 of The Proof with Simon Hill

- Simon

10/01/2026

A new weight-loss drug called retatrutide was tested in a major phase 3 trial called TRIUMPH-1, published today in the New England Journal of Medicine. On the highest dose, participants lost an average of 28.3% of their body weight over 80 weeks – about 32 kg for the typical participant.

Retatrutide is the first triple hormone receptor agonist, acting on GLP-1, GIP, and glucagon. The trial involved 2,339 adults with obesity, and the drug also reduced knee osteoarthritis pain and cut sleep apnoea events substantially. As always, there’s fine print: gut side effects were common, more people stopped on the highest dose, and we don’t yet have data on heart attacks, strokes, or deaths. It’s also not currently FDA-approved, so anything being sold as retatrutide right now is grey market and comes with safety risks. Swipe through for the full picture.

- Simon

09/08/2026

New episode on how people should think about preventing heart disease early in life with Dr Thomas Dayspring and Dr Dan Soffer.

Watch on YouTube or listen on Apple/Spotify.

- Simon

09/01/2026

Do we have a tendency to over-complicate things when it comes to ‘longevity’? I think so and so does today’s guest Dr Deborah Kado - Gerontologist from Stanford University.

Eat well, prioritise sleep, move your body and build proper healthy relationships with friends and family. Focus on consistency rather than perfection. And give yourself grace when it doesn’t go to plan. The human experience is messy, non-linear and finite.

Enjoy yourself (and this episode).

- Simon

08/26/2026

Reversing type 2 diabetes, or at least putting it into remission, is totally possible. In today’s conversation I sit back down with Professor Roy Taylor to discuss the 5 year results of his DIRECT trial on diabetes remission, gestational diabetes, glp-1 agonists and more.

Watch on YouTube or listen on Apple/Spotify (The Proof with Simon Hill).

Professor Roy Taylor MBE is emeritus professor of medicine and metabolism at Newcastle University, and the scientist behind the twin cycle hypothesis and the personal fat threshold. His DiRECT trial showed type 2 diabetes remission is achievable in primary care, and his work is now the basis of the NHS Type 2 Diabetes Path to Remission programme.

Enjoy

Simon

08/11/2026

New episode on fertility, s***m testing and improving s***m health with Michael Eisenberg, MD and Natalie Crawford MD, Fertility

Ep 431 of The Proof with Simon Hill

Enjoy

Simon

07/30/2026

Life of late. S***m chats. Torn ligaments. Anniversary’s of those no longer with us. Birthdays. Newborn energy. Family time. Travel

Life’s short and a lot of things that stress us out and continually occupy our minds aren’t that important. Its mostly noise wearing a convincing costume.

What do you actually want? Focus on that 🫶🏻

07/18/2026

I’ll be presenting at Eudēmonia Summit this November in Florida.

If you haven’t come across it, Eudēmonia has quickly become one of the leading global gatherings in the health and wellness space – less a conference, more a few days spent alongside the voices you want to hear from, spanning a variety of backgrounds, expertise, and views. The speakers don’t all agree with one another – and to my mind that’s a feature, not a flaw. Good ideas hold up in rooms where they’re challenged.

It runs November 5–8 in West Palm Beach, and blends the conversations you’d expect – lectures, panels, Q&As – with the practical side: breathwork, cold exposure, resistance training, and plenty of opportunities to actually move rather than sit in a hall all day.

There’s also the EXPOSŌME – a hands-on showcase of brands working across personalised medicine, wellness tech, and functional nutrition, with live demos and book signings throughout.

I’ll share more on my session closer to the date. If you’re planning to be there, let me know in the comments – would be great to say hello in person.

And yes… will be making sure to get a few games of padel in while I’m on that side of the US 🇺🇸 🎾

- Simon 🙏🏼

07/15/2026

Ready to have your mind blown? Listen to this weeks episode with .fede.amati on the importance of the first 1000 days of life. Part 1 of a 2 part conversation.

Find on - YouTube, Spotify, Apple etc

07/10/2026

This weeks episode of is an incredibly important conversation for anyone wishing to live a long healthy life. Heart disease really should be a disease of the past.

Joining me to walk us through cutting edge cardiac imaging is Dr Campbell Rogers.

Watch on YouTube or listen on Spotify/Apple podcasts - search ‘The Proof with Simon Hill’

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http://www.theproof.com/

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