10/26/2026
🦠 SYPHILIS: Causes, Symptoms, Diagnosis, Treatment & Prevention | NCLEX Nursing Review 🩺📚
Syphilis is a s*xually transmitted infection (STI) caused by the bacterium Treponema pallidum. Early diagnosis and appropriate treatment are essential to prevent serious complications.
🔬 Key Nursing Points:
✅ Cause: Treponema pallidum (spirochete bacterium)
✅ Transmission: Sexual contact with infectious sores and mother-to-baby transmission during pregnancy.
✅ Primary Stage: Classically presents with a painless chancre.
✅ Secondary Stage: Skin rash, including the palms and soles, fever, and swollen lymph nodes.
✅ Latent Stage: No visible symptoms, but infection remains present.
✅ Diagnosis: Blood tests such as VDRL/RPR and confirmatory treponemal tests.
✅ Treatment: Penicillin G is the preferred treatment; the regimen depends on the stage of infection.
✅ Prevention: Safer s*x, regular STI screening, early treatment, and partner testing and treatment.
⚠️ NCLEX TIP: A painless ge***al ulcer is a classic sign of primary syphilis, while a rash involving the palms and soles is associated with secondary syphilis.
📚 Follow NCLEX Success Academy for more nursing concepts, medical terminology, NCLEX practice questions, and high-yield exam tips!
💬 Test your knowledge: Which stage of syphilis is classically associated with a painless chancre? Comment your answer below! 👇