08/26/2026
Pyloric Botox isn’t the gastroparesis treatment that everyone may make it sound like.
The theory makes sense.
The problem is what happens when we test that theory in controlled trials. Unfortunately the data just isn’t there.
And this is an important reminder that “it improved my gastric emptying” and “it improved my gastroparesis” are not necessarily the same thing. This isn’t to say that some haven’t found it helpful!
The pylorus is still an important area of research. We just don’t yet have a reliable way to identify every patient who might benefit.