American Society of Pediatric Nephrology

American Society of Pediatric Nephrology The ASPN is an organization of pediatric nephrologists and affiliated health care professionals.

Our primary goals are to promote optimal care for children with kidney disease through advocacy,
education and research; and to disseminate advances in clinical practice and scientific investigation.

Perioperative severe hemorrhage in pediatric kidney transplantation: frequency, risk factors, and outcomes
06/19/2026

Perioperative severe hemorrhage in pediatric kidney transplantation: frequency, risk factors, and outcomes

Background To characterize severe hemorrhage and determine its frequency, risk factors, and consequences in the perioperative period of pediatric kidney transplantation. Methods Single-center retrospective study of children undergoing their first kidney transplant between 2008 and 2015. Severe hemor...

Review: Biomarkers of kidney involvement in paediatric IgA vasculitis: a systematic review and meta-analysis
06/19/2026

Review: Biomarkers of kidney involvement in paediatric IgA vasculitis: a systematic review and meta-analysis

Background IgA vasculitis nephritis (IgAVN) develops in 20–80% of patients with IgA vasculitis (IgAV), yet diagnosis is often delayed. Readily available biomarkers can help identify patients at risk earlier. Objective To conduct a systematic review and meta-analysis of all available serum and urin...

Review: Clinical complications and anthropometric indicators of chronic kidney disease in a global context: scoping revi...
06/19/2026

Review: Clinical complications and anthropometric indicators of chronic kidney disease in a global context: scoping review

Background Pediatric chronic kidney disease (CKD) is a serious public health problem and represents a considerable burden on health systems, particularly in low- and middle-income countries (LMICs). Despite well-documented global disparities in CKD management, the extent of these differences across....

Review: Update on   and chronic kidney diseases in children
06/18/2026

Review: Update on and chronic kidney diseases in children

Abstract Chronic kidney disease (CKD) is a major global health burden that disproportionately impacts people of recent African ancestry. The discovery of risk variants in the apolipoprotein L1 (APOL1) gene has transformed the understanding of racial disparities in CKD. In particular, APOL1 variants....

Review: Prenatal body fluid analysis in the evaluation of CAKUT
06/18/2026

Review: Prenatal body fluid analysis in the evaluation of CAKUT

Congenital anomalies of the kidney and urinary tract (CAKUT) are the leading cause of chronic kidney disease in children. Although prenatal ultrasound enables early detection, its ability to predict postnatal renal outcome, particularly in bilateral cases, remains limited due to substantial phenotyp...

Weight changes and variability in the first week of life: associations with mortality in extremely preterm newborns
06/18/2026

Weight changes and variability in the first week of life: associations with mortality in extremely preterm newborns

Background In extremely preterm newborns (ELGANs, 

Cardiac adaptation in pediatric kidney transplant recipients with large donor–recipient size discrepancy: a speckle-trac...
06/18/2026

Cardiac adaptation in pediatric kidney transplant recipients with large donor–recipient size discrepancy: a speckle-tracking echocardiography study

Background Pediatric living donor kidney transplantation (KT) with large donor-recipient size mismatch induces a large hemodynamic burden on the child recipient. Although successful KT is known to be beneficial for cardiac function and remodeling, its effects in small recipients with adult donors ha...

Beyond the kidney: prevalence of extrarenal complications and their long-term sequelae in Shiga toxin-producing Escheric...
06/17/2026

Beyond the kidney: prevalence of extrarenal complications and their long-term sequelae in Shiga toxin-producing Escherichia coli hemolytic uremic syndrome

Background Shiga toxin-producing Escherichia coli hemolytic uremic syndrome (STEC-HUS) is a leading cause of acute kidney injury in children, but its systemic nature can lead to extrarenal complications. While long-term kidney sequelae are well-documented, data on the long-term consequences of extra...

Clinical, laboratory, and pathological correlates of crescent formation in biopsy-proven pediatric IgA vasculitis nephri...
06/17/2026

Clinical, laboratory, and pathological correlates of crescent formation in biopsy-proven pediatric IgA vasculitis nephritis

Background Crescent formation is common in pediatric IgA vasculitis nephritis (IgAVN), but its clinicopathological correlates and the significance of crescent burden and activity remain unclear. Methods We retrospectively analyzed 1,280 children with biopsy-proven IgAVN and available crescent assess...

Review: Paediatric chronic kidney disease of unknown aetiology: early-life origins, detection, and prevention
06/17/2026

Review: Paediatric chronic kidney disease of unknown aetiology: early-life origins, detection, and prevention

Chronic kidney disease of unknown aetiology (CKDu) has emerged as a major public health problem in several regions worldwide. While traditionally considered a disease of adults, the latest evidence suggests that CKDu may originate early in life. This review summarises current evidence on the epidemi...

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