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Suvorexant May Ease Symptoms During Opioid Withdrawal TherapyLearn more ->
07/13/2022

Suvorexant May Ease Symptoms During Opioid Withdrawal Therapy

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Small pilot study suggests suvorexant may improve sleep, reduce opioid withdrawal and craving during buprenorphine/naloxone taper

Significant Smoking Cessation Observed With Cytisinicline in Phase 3 TrialLearn more ->
04/28/2022

Significant Smoking Cessation Observed With Cytisinicline in Phase 3 Trial

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The placebo-controlled ORCA-2 study evaluated the safety and efficacy of cytisinicline as a treatment for smoking cessation in 810 adult smokers.

03/31/2022

Mini-Slings for Stress Incontinence in Women

In this randomized noninferiority trial comparing two surgical treatments for stress urinary incontinence in women, mini-slings were noninferior to midurethral slings with respect to patient-reported success at 15 months, and the between-group difference remained similar at 3 years. Dyspareunia was more common with mini-slings.

Learn more -> https://www.nejm.org/doi/full/10.1056/NEJMoa2111815?query=featured_home

03/24/2022

Darolutamide in Metastatic Prostate Cancer

Standard therapy for metastatic, hormone-sensitive prostate cancer is androgen-deprivation therapy, usually with docetaxel. A large, multinational, phase 3 trial assessed the addition of the androgen-receptor blocker darolutamide to standard therapy. At 4 years, survival was higher with darolutamide than with placebo (62.7% vs. 50.4%), with no major differences in the frequency of adverse events.

Learn more -> https://www.nejm.org/doi/full/10.1056/NEJMoa2119115?query=featured_home

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