10/12/2026
High blood pressure in the OR rarely has a one-drug-fits-all answer.
Hydralazine, nitroglycerin, labetalol, esmolol, nicardipine, sodium nitroprusside, phentolamine - each differs in mechanism, onset, duration, and titratability.
The key is matching the agent to the clinical situation:
• How quickly does the pressure need to come down?
• Is tachycardia or bradycardia present?
• Do you need a short, titratable effect?
• What does the patient’s underlying physiology allow?
Save this quick comparison for your next OR case.
Check anesthesia medications, dosing, and clinical details in NYSORA’s Anesthesia Assistant App: https://nysora.onelink.me/D0FL/v4byscc8