Hillary Lin, MD

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Hillary Lin, MD

Stanford-trained physician focused on evidence-based longevity medicine: labs, medications, prevention, risk, and what the science actually supports.

Founder of CareCore. Host of The Longevity Show. I'm Dr. Hillary Lin, a Stanford-trained internal medicine physician and longevity clinician. I use this page to make longevity medicine more rigorous and less hype-driven: what labs can and cannot tell you, when medications or supplements make sense, how to think about prevention, and where the evidence is thin. For clinic support: support@hillaryli

nmd.com. For CareCore: [email protected]. CareCore builds clinically governed protocol infrastructure for evidence-based care and health products. This page is Hillary Lin, MD, so the center of gravity here is physician judgment, science translation, and practical prevention — not miracle claims or one-size-fits-all optimization.

06/10/2026

“Non-toxic” is not a material — it’s a marketing word.

If you’re choosing cookware, start with the surface touching your food, not the cleanest-sounding label.

This carousel breaks down PFOA-free vs PFAS-free vs PTFE-free, ceramic, and titanium claims, plus when I’d replace a worn nonstick pan.

Full guide: https://hillarylinmd.com/guides/safe-nonstick-cookware

06/02/2026

The Enhanced Games were pitched as a cleaner version of a messy reality: let the drugs be visible, supervise them medically, and measure what happens.

That part is interesting.

But the results did not give us the simple story people wanted.

One swimmer went faster than the official 50m freestyle record, but the mark was unofficial: drug-permitted event, banned suit tech, not ratified like a normal world record. Most records did not fall. Several reported non-enhanced athletes still won.

That does not mean steroids are fake. Testosterone, growth hormone, stimulants, EPO, and other performance drugs can change real physiology: muscle, recovery, arousal, oxygen-carrying capacity, training tolerance.

But sport is not a blood test. A race result also depends on talent, event fit, training history, timing, injury risk, nerves, equipment, and side effects.

This is the longevity lesson too: a better lab number is not automatically a better health outcome. Faster recovery is not automatically better long-term function. Medical supervision is not the same as proof of safety.

Wrong question: do these drugs work? Some do. Better question: what outcome are we trying to improve — and what tradeoff are we accepting to get there?

Follow for longevity medicine without hype.

Sources: Enhanced ASCEND001/ClinicalTrials.gov, BBC/AFP, World Aquatics, NBC/ABC reporting, and selected PubMed anchors.

05/29/2026

The 1% Longevity Rule:

150 minutes of exercise per week sounds like one more impossible thing.

But 150 minutes is about 1% of your week.

That does not mean everyone’s schedule is easy. It means the question gets more useful.

Where can the 1% go?

A walk between meetings. A short strength session. Exercise snacks. A few protected blocks across the week.

Then the mix matters: strength training, low/moderate aerobic work, a little higher-intensity work if you are ready for it, and enough recovery to actually adapt.

For longevity, the goal is not the hardest possible week.
It is a training rhythm you can repeat.

From my conversation with Kyle Gonzalez on The Longevity Show (link in bio).

05/28/2026

Don't start with NAD+, peptides, or the latest mitochondrial stack.

Those tools may have a place, but not at the bottom of the pyramid.

The base is still the part your body has to adapt to:

- aerobic work you can repeat
- strength training
- sleep
- protein and hydration
- recovery
- the right training dose

Then you can layer in intervals, supplements, gadgets, and more advanced protocols.

If the base is weak, the stack is just decoration.

From my conversation with Kyle Gonzalez on The Longevity Show (link in bio).

05/18/2026

Hormone optimization got messy.

I am not anti-hormone. Testosterone therapy can be appropriate. Menopausal hormone therapy can be life-changing for the right patient. Thyroid replacement matters when someone is hypothyroid.

What I am against is turning every normal-range lab into a subscription.

A reference range is a starting point. It does not know whether you sleep, ovulate, overtrain, drink nightly, eat enough protein, have sleep apnea, take medications that affect the axis, or are in perimenopause.

A real hormone plan has an indication, baseline labs, contraindication review, monitoring, a symptom target, and a stopping rule.

Without that, it is just vibes with a lab order.

Save this if you are being pitched hormone optimization and want better questions to ask.

05/15/2026

Your LDL is not the whole cholesterol story.

For a long time, the lipid conversation was flattened into one question: “Is your LDL high?”

But that misses a lot.

ApoB helps estimate the number of atherogenic particles. Lp(a) can reveal inherited risk that lifestyle usually does not fix. Family history, metabolic health, blood pressure, smoking history, and sometimes imaging all change how aggressive the plan should be.

And the treatment ladder is much broader than “statin or nothing.”

Statins are still foundational for many higher-risk patients. Ezetimibe is a boring, inexpensive, underused add-on. PCSK9 inhibitors and inclisiran can be useful escalation tools when risk is high or targets aren’t being reached.

The point is not to medicate everyone.

The point is to match the intensity of treatment to the actual risk pattern.

And if your lipids stay high despite doing the “right” lifestyle things, that does not mean you failed at health. Sometimes biology needs a tool.

Save this for your next lipid visit, especially the question slide.

Educational only; talk with your clinician about your own risk and treatment options.

05/11/2026

I get why pickleball became the sport people associate with aging well.

Not because it is magical. Because one rally asks for a surprisingly useful mix of physiology: fast force, braking, balance, reaction time, visual tracking, short cardio bursts, and social play.

That mix matters because aging is often a loss of reserve. Less muscle. Slower reactions. Worse braking. Lower aerobic margin. Less tissue tolerance. Less confidence moving in the real world.

The evidence is interesting, but it is not a miracle claim. Pickleball can reach moderate-to-vigorous intensity in older adults. One small supervised 8-week trial in pre-frail adults found improved pre-frailty status and functional fitness after 8 weeks.

That does not mean pickleball prevents dementia, fractures, falls, osteoporosis, or death.

It means it is a useful template.

If you love it, play it well. Add strength training, calf and Achilles prep, balance work, bone-loading where appropriate, and progressive training.

If you hate it, copy the demands instead:

- move sideways
- stop quickly
- react to something unpredictable
- build aerobic reserve
- choose one active thing with enough fun or social pull that you keep doing it

That is the bigger point: longevity training should build reserve you can actually use.

Full essay: https://newsletter.hillarylinmd.com/p/pickleball-ultimate-longevity-sport

05/06/2026

Your longevity supplement stack is probably too crowded.

I see this constantly: $300 to $500/month in capsules, built from podcasts, influencer protocols, and one very impressive mouse study.

The filter I use is much less exciting:
human evidence, safety, dose, and a reason to keep taking it.

Creatine is boring and unusually defensible. Omega-3 can be useful, but dose and form matter. Magnesium helps when intake is low or the story fits. NMN/NR are interesting, but raising NAD is not the same as proving longer life in humans.

What I am much less impressed by: resveratrol, most proprietary blends, "sirtuin activators," and anything with 15 ingredients dosed like fairy dust.

The goal is not a more advanced stack. It is a smaller one you can actually justify.

Save this before your next supplement order.

05/01/2026

Are you paying a "Longevity Premium" for basic wellness products?

We are officially in the era of Longevity Washing. Marketers have realized a simple truth: if you swap the word "Wellness" for "Longevity," you can charge a massive markup. Suddenly, a standard cold plunge is being sold as "cellular rejuvenation."

The market for high-end "Longevity Clinics" reached $5.35 Billion in 2025, but the truth is, real longevity is usually pretty boring. It’s VO2 Max over cryo-chambers. It’s managing your ApoB and blood pressure over a $25,000 full-body scan.

I broke down the Wash vs. the Reality across the cosmetics, fitness, nutrition, and medical industries in today's post.

Take a look at the slides—have you fallen for any of these marketing traps? (I know I've been tempted by the packaging a few times!). Let me know your thoughts.

04/30/2026

A $4 cholesterol drug reduces Alzheimer's risk by 7x.

It's been available since 2002. Almost nobody's prescribing it for dementia prevention.

That's ezetimibe — one of 10 generics with serious mortality data that almost never comes up in a longevity conversation.

Swipe through the full carousel 👇

• Tadalafil ($15-30/mo) — yes, the ED drug. A 2024 study screened 407 drugs for all-cause mortality. Near the top.
• Women's HRT — the WHI study scared women away for 20 years. Wrong patients, wrong timing, wrong hormones. Women starting within 10 years of menopause: consistent all-cause mortality reductions.
• Colchicine (0.5mg) — FDA approved in 2023 to prevent cardiovascular events. Almost nobody outside cardiology knows this.
• Rapamycin — the only drug extending lifespan in every major animal model. Human trials actively running.

Total stack: ~$50/month.

Which one surprised you most? Drop it below — I read every comment.

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https://hillarylinmd.com/

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