10/27/2026
As his Parkinson’s disease progressed over 12 years, everyday activities became battles for Stan Au. His hands shook so badly that he struggled to hold utensils and couldn’t sign his name. After consulting multiple doctors, hope emerged when they met Dr. Harini Sarva, a neurologist specializing in movement disorders at Weill Cornell Medicine and NewYork-Presbyterian Hospital. “Dr. Sarva is very thorough, and she took us more seriously,” his wife Pam says. “And she is the one who recommended the trial.”
That clinical trial—using focused ultrasound waves to target disrupted brain pathways contributing to Parkinson’s symptoms—provided immediate relief to Stan without invasive surgery, 67.
“It’s been a dramatic influence on my life,” he says, noting he still benefits from reduced tremors four years later.
The outpatient treatment starts with shaving the patient's head to prevent ultrasound waves from scattering. Next, the patient wears a helmet and lies inside an MRI machine. The helmet directs a thousand beams of ultrasound focused on a tiny brain target, like spokes on a bicycle wheel coming together at one point.
“Parkinson’s affects about one million Americans, and while there is no cure, ultrasound treatments offer patients a better quality of life, reducing some of the most disabling effects of the disease,” said Dr. Michael G. Kaplitt, a neurosurgeon at Weill Cornell Medicine Neurological Surgery and NewYork-Presbyterian Hospital.
The Food and Drug Administration approved focused ultrasound to treat tremor in Parkinson’s disease on one side of the brain 8 years ago. Because the body’s right and left sides are controlled separately, patients may need two treatments, one on each side. Last year, the FDA approved focused ultrasound treatment for both sides of the brain, spaced six to nine months apart based on Dr. Kaplitt’s clinical trial results. Medicare began covering the bilateral procedure in March this year.
Stan benefited from treatment on both sides of the brain without serious adverse effects. “I have less stiffness, better coordination, and I am more active—even playing pickleball again,” he says.
The mobility he has regained has also given Stan something especially meaningful to look forward to: he plans to walk his daughter down the aisle at her wedding next fall.