05/25/2026
24,409 blocks. 23 complications. All from central blocks. Zero from peripheral. One paper. 1996.
Giaufre published the first large prospective registry of pediatric regional anesthesia: 38 institutions across France, Belgium, and Italy, tracking every block for a full year. The finding everyone remembers is that peripheral nerve blocks had zero complications, while central blocks carried all the risk.
But read the paper, not the citation.
The “peripheral blocks” in 1993 were mostly pe**le blocks and tracheal sprays. Only 1,393 of the 9,396 were true extremity nerve blocks. There was no ultrasound. Central blocks were 61.5% of all regional anesthesia. The menu was caudals, epidurals, and a handful of axillary and femoral blocks. Fascial plane blocks didn’t exist. Voluntary reporting means underreporting is possible. And half the complications came from wrong equipment, preventable with gear that exists today.
Here’s what I think matters most about this paper, though.
The specific numbers are outdated. The blocks are unrecognizable. The methodology has been superseded by PRAN and more than 100,000 blocks with institutional-level tracking. But the directional signal, favor peripheral when the anatomy allows, confirmed where modern practice was already heading. By 2010, Ecoffey’s ADARPEF follow-up showed central blocks had dropped from 61.5% to 34%. Walker confirmed the safety profile at massive scale in 2018. The field listened. The field is still listening.
That’s what a classic does. It doesn’t need to be perfect. It needs to ask the right question.
If you can get to Montevideo in October, LASRA’s hands-on workshop is where this kind of evidence meets practice: real blocks, real guidance, deliberate repetition at the table. If you can’t make it, baby-blocks.com is free and built to help you take that first step on your own.
Giaufre E, Dalens B, Gombert A. Anesth Analg. 1996;83:904-912.
Ecoffey C, Lacroix F, Giaufre E, et al. Pediatr Anesth. 2010;20:1061-1069.
Walker BJ, Long JB, Sathyamoorthy M, et al. Anesthesiology. 2018;129(4)721-732.