Vibrant Gastro

Vibrant Gastro Vibrant is the innovative, drug-free pill for Chronic Idiopathic Constipation (CIC) in adults.

It's FDA-cleared to help you reclaim your comfort and quality of life. Experience the freedom of smooth, regular movements without relying on medications.

"While traditional prescription therapies often carry high rates of diarrhea, abdominal pain, and bloating, the Vibrant ...
02/13/2026

"While traditional prescription therapies often carry high rates of diarrhea, abdominal pain, and bloating, the Vibrant System™ demonstrated extraordinary tolerability:

Only 0.64% of patients reported diarrhea — a rate dramatically lower than that typically seen with pharmacologic treatments for CIC.

Less than 2% reported abdominal pain, and just 1.3% reported bloating or distention. :

About Vibrant Gastro Vibrant Gastro is a health‑tech company pioneering drug free therapeutics for gastrointestinal disorders. Its first‑in‑class product, the Vibrant System™, is a prescription vibrating capsule that provides a non‑pharmacological treatment for chronic idiopathic constipat...

“Number one, we know that it works,” Darren Brenner, MD, a professor of medicine and surgery in the division of gastroen...
12/15/2025

“Number one, we know that it works,” Darren Brenner, MD, a professor of medicine and surgery in the division of gastroenterology at Northwestern University and serves as director of the Neurogastromotility and Interdisciplinary Bowel Dysfunction programs, told HCPLive. “We now have multiple data points showing that [Vibrant] can be effective, from the phase 3 trials that show that it could significantly improve one to two complete spontaneous bowel moments a week in patients to now our data showing that 3 to 6 months later, people are doing very well for multiple endpoints.”

Of note, abdominal pain, bloating, and nausea were each reported by

Brenner describes shortcomings of pharmacologic CIC options and reviews real-world data on the Vibrant System’s benefits in this context.

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