Annals of Internal Medicine: Clinical Cases

Annals of Internal Medicine: Clinical Cases A partnership between the American College of Physicians and the American Heart Association, AIMCC i

Read online for free now: Cold Agglutinin Syndrome Caused by Mycoplasma pneumoniae in a Recipient of a Renal Transplant ...
06/19/2026

Read online for free now: Cold Agglutinin Syndrome Caused by Mycoplasma pneumoniae in a Recipient of a Renal Transplant https://bit.ly/4oJZ7M8

A 77-year-old patient with severe obstructive sleep apnea developed exploding head syndrome (EHS), a condition character...
06/18/2026

A 77-year-old patient with severe obstructive sleep apnea developed exploding head syndrome (EHS), a condition characterized by frequent, distressing “explosion” sensations at sleep onset. Treatment using CPAP dramatically reduced EHS episodes. This case supports systematic screening for sleep-disordered breathing in patients with EHS, especially those at risk for obstructive sleep apnea. https://bit.ly/4eRnFiI

A 34-year-old woman with an increasingly swollen abdomen thought she may be pregnant, but imaging revealed a massive sto...
06/17/2026

A 34-year-old woman with an increasingly swollen abdomen thought she may be pregnant, but imaging revealed a massive stool mass with high-density nonfecal material due to the compulsive eating of clay ( ). Read the full case report for free: https://bit.ly/4ef02k1

A new case report describes a patient with chronic untreated hepatitis C who experienced worsening shortness of breath a...
06/12/2026

A new case report describes a patient with chronic untreated hepatitis C who experienced worsening shortness of breath and low oxygen saturation that improved when lying flat. Intrapulmonary shunting confirmed by contrast echocardiography led to a diagnosis of hepatopulmonary syndrome. Read more here: https://bit.ly/3QaHEj3

Kikuchi-Fujimoto disease (KFD) is a rare, benign, self-limiting hyperinflammatory condition that has been described in a...
06/11/2026

Kikuchi-Fujimoto disease (KFD) is a rare, benign, self-limiting hyperinflammatory condition that has been described in association with autoimmune disease. A new case report describes, to the authors' knowledge, one of the first reports of KFD occurring in association with dermatomyositis, a rare autoimmune condition characterized by muscle inflammation. Read the full text for free: https://bit.ly/4aK3mBk

A patient with hemophilia A experienced severe internal bleeding caused by a small duodenal gastrointestinal stromal tum...
06/10/2026

A patient with hemophilia A experienced severe internal bleeding caused by a small duodenal gastrointestinal stromal tumor. When endoscopic and radiologic interventions were unsuccessful, rapid factor VIII replacement and surgery were required. The case highlights the importance of individualized, multidisciplinary care in managing complex gastrointestinal bleeding in patients with clotting disorders. https://bit.ly/4vA7MTj

An 80-year-old man taking the minocycline for recurrent prosthetic joint infections developed blue-gray hyperpigmentat...
06/09/2026

An 80-year-old man taking the minocycline for recurrent prosthetic joint infections developed blue-gray hyperpigmentation of both legs after 15 months. While the discoloration is benign, clinicians should be aware of this side effect with prolonged use of minocycline and engage in shared-decision making with patients before initiating therapy. https://bit.ly/4xiLpn6 Institute of Human Virology

While is highly effective for weight loss, data on its potential association with thrombosis is limited. A new case re...
06/05/2026

While is highly effective for weight loss, data on its potential association with thrombosis is limited. A new case report describes extensive abdominal vein thrombosis following treatment initiation of tirzepatide in a 56-year-old-man. This case highlights how rapid weight reduction may act as a precipitant for venous thrombosis and underscores the importance of careful risk assessment and individualized safe weight loss goals. https://bit.ly/3QousqK

CPAP is a cornerstone therapy for obstructive and is generally safe, but rare complications can occur. A new case repo...
06/04/2026

CPAP is a cornerstone therapy for obstructive and is generally safe, but rare complications can occur. A new case report highlights hydropneumothorax, the abnormal presence of air and fluid in the space between the lung and chest, in a patient with underlying lung vulnerability. This case underscores the importance of monitoring and periodically reassessing settings. https://bit.ly/4uSOetD

A new case report describes nutcracker syndrome, a rare vascular disorder, in a previously healthy man who began passing...
06/03/2026

A new case report describes nutcracker syndrome, a rare vascular disorder, in a previously healthy man who began passing blood clots in his urine after a 20-pound weight loss. Conservative management, including weight gain and strength and flexibility training, led to a favorable outcome. Read the full text of this autobiographical case report, where Cameron M. Quon, MD is both the author and patient described, for free: https://bit.ly/4vw8EZs

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