06/03/2026
In 2017, a PSA reading of 7.0 ng/mL put Thomas Seager, PhD on a path toward biopsies, surgery, and radiation. He chose a different path: a metabolic protocol built around daily cold water immersion and cycling through ketosis.
Eight years later, his PSA is 1.8 ng/mL.
The protocol is specific. An ice bath at 34F for 2 to 4 minutes, six days a week. A 24-hour fast once a week. Carbohydrate restriction on most days, cycling in and out of ketosis rather than maintaining it as a fixed state. The biological rationale is grounded in research on cold thermogenesis and cancer metabolism. Cold exposure deprives tumor cells of the glucose they depend on for growth. Ice baths stimulate endogenous ketone production, which carries its own inhibitory effects on tumor metabolism.
Three men have since reported similar outcomes under physician supervision. PSA reductions from 12.1 to 2.2, from 9.8 to 1.8, and from 14.6 to 2.6, all after incorporating cold plunge therapy. One of those men spent eight months resisting his doctor's push for surgery while the protocol worked. His tumor was touching the prostate capsule. The metastasis his doctor warned about did not occur.
One man's PSA went up. That result is part of the record and is being monitored.
The assumption that high testosterone accelerates prostate cancer is not supported by current research. Studies published in 2014 found no increased cancer risk even when testosterone was doubled in men and women. Seager's protocol raised his testosterone to levels rare for his age group. His prostate health continued to improve.
This is not a prescription. Every body is different, and nothing here constitutes medical advice. It is a documented protocol with measurable outcomes, shared for men who want to understand their metabolic options.
Ice baths, intermittent fasting, and ketosis reduced prostate specific antigen (PSA) without biopsy, surgery, chemotherapy, or radiation.