Unraveling Candidiasis

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Unraveling Candidiasis Little Spirit Books presents "Unraveling Candidiasis, The Perplexing Puzzle of Medical Maladies."

10/13/2026

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10/13/2026

The Fibromyalgia—Candidiasis Connection! (And it mostly starts within the gut.)

[This is an educational article by Marc J. Bielski, M.D. (author of “Unraveling Candidiasis”) and not AI generated or spam.]

• Disease-causing yeast within the gut create bowel issues (IBS, IBD, and more).

• With time, their presence will progress to invasive candidiasis within the gut wall/tissues, with biofilms.

• This is likely to escalate to invasive candidiasis, involving their entry and colonization into the bloodstream, creating widespread bodily harm, with their infectious, allergic, and inflammatory effects.

Fibromyalgia syndrome is a condition that typically involves pain.

About 4 million adults suffer with fibromyalgia in the United States, and almost 1 in 20 people, or 5 percent, are affected worldwide. It is a chronic condition in people of all ages, but most sufferers are diagnosed during middle age. Women are twice as likely as men to have it. And its incidence has only increased since the post-COVID pandemic.

Since it shares many similarities with arthritis, these two conditions are often confused with one another. Having one does not exclude the other, and people can have both. It is possible to tell these two conditions apart.

Typically, fibromyalgia involves neck and shoulder pain, morning stiffness, fatigue, and sleep disturbances. Although these symptoms can be present in an arthritis sufferer, fibromyalgia pain is usually associated with someone’s muscles and connective tissue, not their joints. Therefore, unlike arthritis, diagnosing fibromyalgia depends on the minimum number of body points that are tender when touched.

Most medical experts believe fibromyalgia syndrome is closely related to chronic fatigue syndrome, and both are thought to represent manifestations of the same disorder. Since there is a chronic fatigue–fibromyalgia syndrome connection and a candidiasis–chronic fatigue connection (chapter 15), there must be a candidiasis—chronic fatigue-fibromyalgia syndrome connection.

Research reveals the involvement of disease-causing yeast in fibromyalgia syndrome.

Using the citric acid cycle of metabolism, disease-causing yeast and other fungi can produce numerous harmful metabolites, including citramalic acid, tartaric acid, 3-oxoglutaric acid, and carboxycitric acid.

Among these, tartaric acid is specifically known to be destructive to muscle tissue (as well as citramalic acid).

It is thought, therefore, that the overproduction of tartaric acid by disease-causing yeast (and other fungi) in susceptible people causes muscle damage of fibromyalgia syndrome.

Furthermore, for many reasons, chronic candidiasis can promote excesses of lactic acid, a substance that can make muscles more prone to fatigue.

Some physicians believe that fibromyalgia syndrome is related to a decreased flow of lymph through the lymphatic system. Lymph is a fluid created within all the tissue spaces of the body. After its formation, it flows into small vessels that lead to larger vessels and eventually enters the blood. Lymph contains proteins (serum albumin, serum globulin, serum fibrinogen), salts, organic substances (urea, creatinine, neutral fats, glucose), water, and immune cells called lymphocytes. Decreasing the flow of lymph increases the amounts of these substances within the affected muscles, leading to increased pressure and pain within these areas.

It is not known whether candidiasis can decrease lymphatic drainage, but the presence of citric acid cycle metabolites is certain to exacerbate this condition as well as the inflammation that accompanies the infectious and allergic contributions of disease-causing yeast.

The evidence supports a candidiasis–fibromyalgia syndrome connection, especially when the chronic presence of disease-causing yeast adversely affects the nervous (chapter 10), endocrine (chapter 11), and immune systems (chapter 14).

One or more infectious invaders (harmful molds, bacteria, and parasites) may actively participate and need to be addressed accordingly. And holistic physicians also consider the adverse contributions of toxic heavy metals because many sufferers improve with detoxification.

Therefore, a comprehensive approach to diagnosis and treatment is usually required. So, instead of having no hope, fibromyalgia syndrome sufferers now have information to guide them towards a way to regain their wellness.

MJB M.D.

Gastrointestinal candidiasis will progress to invasive candidiasis (leaky gut syndrome)!  -- Irritable Bowel Syndrome (I...
10/10/2026

Gastrointestinal candidiasis will progress to invasive candidiasis (leaky gut syndrome)! -- Irritable Bowel Syndrome (IBS) sufferers, please consider...

As the number of infectious invaders within the gut increases, inflammation within the gut wall and tissues occur.

They become irritated, swollen, impaired, and even injured. As a result, the gut wall becomes weakened and increasingly fragile, making it easier to disturb with each additional insult. Eventually, as the insults accumulate, the gut wall can be breached, which allows inappropriate substances to enter the tissues, while fluid and other substances can leak out.

Damage to the gut wall does not happen spontaneously.

Instead, disease-causing yeast readily participate.

Under optimal conditions, when they are well-fed, disease-causing yeast typically remain in their less-aggressive ovoid form.

However…

When their environment is compromised, some disease-causing yeast can transform into a more aggressive, invasive form called a mycelium, with a main body and numerous, extending branches called hyphae or pseudo-hyphae, like a tree-trunk and its branches.

Even though the ovoid form can enter the gut wall and tissues when its survival is at stake, research reveals the mycelial form is much more effective at invading the gut wall; it produces enzymes that digest protein and other components within the gut wall, allowing it to more easily invade into the gut wall to obtain nutrition. (See the references for Chapter 4 at Amazon, “read sample”)

The mycelial form of disease-causing yeast can digest its surrounding tissue, creating tiny “holes” in the gut wall that allow undigested food particles and other inappropriate substances to leak through, a condition called leaky gut syndrome.

In return, the wall and mucous membranes can become irritated, impaired, injured, and even damaged, from microscopic to grossly visible, localized, patchy, or widespread.

Depending on the location and severity, colonization and invasion can cause or exacerbate one or more gastrointestinal problems, including oral thrush, esophagitis, gastritis, duodenitis, ulcers, irritable bowel syndrome, inflammatory bowel disease, colitis, spastic colon, and proctitis.

In most candidiasis sufferers, their gastrointestinal candidiasis will progress to invasive candidiasis sooner or later. Therefore, a comprehensive approach to diagnosis and treatment is usually required.

MJB M.D.

Attached, original graphic slide: From “Unraveling Candidiasis: The Perplexing Puzzle of Medical Maladies” – Chapter 4: Gastrointestinal Problems, page 97

10/09/2026

"Unraveling Candidiasis"
was created to explain this escalating medial problem!

10/07/2026

1 disease-causing yeast = 0
Billions of disease-causing yeast
within your gut and body creates illness!

10/06/2026

Rather than fixing a crack,
make the effort to create a new foundation for your wellness.

10/06/2026

The microorganisms that live within our body create an environment for
our wellness or illness.

10/06/2026

Candidiasis – An Ever-Increasing Medical Condition! (An Update and Thoughts to Consider)

(This is an article by Marc J. Bielski, M.D. (author of "Unraveling Candidiasis) and not AI generated or spam.)

More people are developing symptoms and illness from candidiasis every day, especially post-COVID. The sufferers are increasing, not decreasing!

Get a “live blood cell” analysis and you’ll know what’s living within your blood.

Is Live Blood Analysis a valid health screening tool? Yes, just search the links.

If the number of mild sufferers was truly appreciated, candidiasis would be immediately classified as an epidemic. Instead, it continues to be ignored, ridiculed, and even maligned.

According to mainstream medicine, candidiasis is an infection with Candida albicans, although they do consider a few other Candida-species organisms to be problematic.

Yet, it’s not “black-or-white” because a variety of disease-causing yeast, mold, bacteria, and parasites consistently collaborate to contribute their harm in causing disease and illness within human beings.

Yet, many mainstream physicians and the pharmaceutical industry will say, “It’s normal to have some fungus living within your blood.”

I’ll counter WHY?

Why are disease-causing yeast considered to be “normal” inhabitants within our blood (and tissues) when their primary purpose is to live on “dead, decaying plant matter and insects as well as on other surfaces and forms of life.”

And how did they get into our blood in the first place?

And if our immune system is doing its job, why are these fungal organisms continuing to exist within our blood and body?

And how is their persistent presence harming our wellness?

With all the patients that I’ve been asked to help during the past few years as a consultant, and my 40+ years of clinical practice, the answers depend on your perspective of wellness.

Major Point: There is a Difference between the Art of Medicine and the Science of Medicine.

An incredibly famous quote is, “I think, therefore, I am.” The medical version for doctors translates; “I think, therefore, I practice.” This emphasizes their confidence in their mental abilities and knowledge. Turning it around, the quote further transforms into “I practice; therefore, I think.”

So, you would believe that every medical decision involves some mental effort.

If this were the case, why do most patients receive treatment like they are traveling along an assembly line?

Why does it seem like people are being treated by a “plumber just fixing their pipes?”

Studies reveal that the average office visit only lasts about six minutes, or shorter. If a patient’s illness has been seen before, most doctors know exactly what to do for it—no arguments, questions, discussions, ifs, ands, or buts. Undeniably, this often precludes freethought from entering the management process.

And with the AI revolution, aimed to produce one or more “magic pill” drugs that treat specific physical issues, this creates a disconnect from human whole-body wellness.

Why?

It negates the art of medicine that addresses the entire person, including their physical body disturbances, and their psychological wellbeing, and why they became sick physically, emotionally, and mentally.

In other words, is our illness just physical?

Or does it have emotional and mental aspects that contribute to our wellness or ill health?

The Infection: Candidiasis involves the colonization with one or more species and strains (variants) of disease-causing yeast.
Typically, in most sufferers it’s a mixed infection, with numerous pathogenic and problematic disease-causing yeast, cooperating to create an internal myco-(fungal)-biome that establishes an environment for many pathogenic microorganisms to synergistically co-create biofilms.

In contrast, the gut is an open environment for anything that’s ingested, including a multitude of infectious invaders, including disease-causing yeast, parasites, pathogenic bacteria, harmful molds, and viruses. These include their blatant and subclinical contributions to cause internal and systemic harm within the body.
Their adverse effects depend on their ability to disrupt the areas they colonize, the metabolites they produce, whether or not they have enzymes that can digest into and through the gut wall (and other epithelial tissues, including the respiratory system and genitourinary system), and more.

In contrast to mainstream medical thinking, an infection with any species and strain (variant) of disease-causing Candida-species organism is also candidiasis. In fact, there are 8 major and 17 less prominent disease-causing yeast, and an infection with any of these microorganisms can cause illness, and other members are being revealed as they rise to prominence; e.g. Candida aureus.

And post-COVID, being a consultant for numerous people with this problem, mixed infections are escalating and ever more prevalent than the simple “candidiasis sufferer” seeking help 30-plus years ago.

From my perspective, most people are suffering with “atypical candidiasis” - to describe the yeast-related illness that is caused by the less prominent disease-causing yeast. People with atypical candidiasis have infections with, as examples, Rhodotorula-species organisms and Saccharomyces cerevisiae.

And compared to someone infected with the major disease-causing yeast, people with atypical candidiasis are not usually as sick, making their infection difficult to detect and understand.

Candidiasis is a Complex, Multi-Systemic Condition: It can adversely affect the nervous, endocrine (hormone), and immune systems and it involves three stages:

1. Gastrointestinal candidiasis occurs when disease-causing yeast colonize the gut interior.

2. Invasive candidiasis starts when the disease-causing yeast invade into the gut wall and colonize it.

3. Systemic candidiasis involves the disease-causing yeast progressing to invade and enter the blood, where they can travel throughout the body and take up residence wherever conditions permit. Disease-causing yeast can also gain access to the lungs and invade into and through the respiratory tissues.

Candidiasis-related Allergies: Simply put, candidiasis is an infection with disease-causing yeast and their allergic consequences, and an abundance of their inflammatory processes.

Some healthcare practitioners accept their allergic contributions, but most only look for antibody-mechanisms related to immunoglobulin E (IgE). Although IgE is accepted as the antibody participating in allergies, about half of all allergies do not involve IgE (or other antibodies).

When allergies are considered, most practitioners typically look for sensitivities and hypersensitivities to foods, environmental substances, or chemicals.

Few physicians consider allergies related to the presence of disease-causing yeast and harmful molds. This oversight ignores most candidiasis sufferers because clinical experience reveals they often have strong allergies to numerous disease-causing yeast and harmful molds. Therefore, it is important to test for these allergies and, when identified, administer desensitization (allergy) immunotherapy, using injections or drops.

The Message: A comprehensive holistic-integrative medical approach to diagnosis and treatment will produce the best long-term health benefits.

Since candidiasis is an infection with one or more species of disease-causing yeast, and no one antifungal medication or herb can kill every species, a layered approach to treatment is often needed. Moreover, in a large percentage of cases, especially people with moderate to severe illness, there are one or more participating infectious allies (harmful parasites, bacteria, molds, and/or viruses) that need to also be revealed and appropriately treated.

In addition, candidiasis is an infection with allergic consequences, including abundant inflammation. Both the infectious and allergic aspects must be addressed. Most candidiasis sufferers have sensitivities and hypersensitivities (allergies) to numerous disease-causing yeast and harmful molds.

As a result, conservative or unsound approaches are virtually guaranteed to provide inadequate health benefits. Therefore, to effectively combat candidiasis, it is essential to see and align all the pieces of the candidiasis puzzle.

MJB M.D.

09/30/2026

Candidiasis has become a
mixed fungal infection,
with many layers to treat!

09/21/2026

Chronic Fatigue and candidiasis!

And, if you have long-COVID syndrome…

If you have been diagnosed with chronic fatigue syndrome (CFS), your fatigue must have been present for at least six months. CFS sufferers do not feel energized, even after sleeping for hours and hours. Many sufferers spend exceptional amounts of time in bed.
Some sufferers are likely to require lengthy and frequent periods of rest just to survive, as minor exertions can sap their strength and deplete their remaining energy. Depending on someone’s responsibilities and social support, CFS can range from disturbing to debilitating to devastating.

If you are a CFS sufferer and would like to regain your energy, please consider candidiasis might be a part, and possibly a major part, of your lack of energy.

The medical-scientific studies and clinical evidence support a candidiasis-CFS connection!

Sub-clinical gut-blood-tissue infections with fungal organisms are on the rise, but you wouldn't know this even exists because mainstream pharmacology is focused on treating symptoms, not moving people towards wellness.

Rather than being a mysterious illness, candidiasis-minded physicians know that CFS is a symptom strongly associated with chronic candidiasis.

Since CFS sufferers and candidiasis sufferers often have identical disturbances, CFS is a manifestation of candidiasis that involves severe fatigue.

In short, most CFS sufferers are really candidiasis sufferers, although there are exceptions. (For example, heavy metal toxicity, pesticide poisoning, and so on.)

To make matters worse, disease-causing yeast may be assisted by other infectious invaders, including harmful parasites, bacteria, molds, and/or viruses.

Obviously, the more infectious invaders present, the greater the toll it takes on someone’s body.

How does candidiasis cause CFS? There is no one specific way.

Yet, candidiasis and CFS are primarily metabolic (chemical) and immune system disorders.

The presence of an infection with disease-causing yeast can suppress, and even depress, the immune system, allowing persistent viral infections to continuously harm the body (chapter 14).

Disease-causing yeast produce harmful substances that are injurious or poisonous to the body, especially the liver. In turn, this compromises the liver’s ability to detoxify harmful substances and provide sufficient energy.

Impaired liver metabolism can promote abnormal glucose tolerance (glucose intolerance), hyperinsulinism, and hyperlipidemia (chapter 14).

Moreover, altered liver functioning will indirectly affect other metabolic processes and pathways.

Any or all of this can impair or injure the functioning of the mitochondria within the cells of the body, especially the liver. Since these intracellular organelles are the cell’s power stations, a mitochondrial disturbance decreases the body’s ability to generate enough energy, which additionally disturbs numerous other metabolic processes.

Candidiasis can cause other problems that contribute to fatigue:

• It can instigate and promote a variety of sensitivities and hypersensitivities, leading to inflammation and allergies (chapter 16).

• Its infectious and allergic consequences can induce an abundance of inflammation, localized and systemic.

• The colonization of disease-causing yeast can establish conditions that encourage malabsorption and nutritional deficiencies (chapter 4), making it difficult to function and generate sufficient cellular energy.

• Their presence increases the generation of harmful oxygen-based free radical reactions with their accompanying cellular insults and injuries (chapter 7).

• Immune impairments may precipitate autoimmune activities (chapter 14) that cause cellular or glandular stimulation, inhibition, or destruction, promoting substantial disturbances.

• Candidiasis can directly or indirectly cause endocrine (hormone) dysfunction, suppression, or exhaustion of the pituitary gland, thyroid gland, parathyroid glands, adrenal glands, and/or s*x glands; any of these can contribute to fatigue (chapter 11).

• Candidiasis can cause neurological disturbances (chapter 10); these frequently involve neurotransmitter abnormalities that directly disturb the brain’s functioning and indirectly disturb the rest of the body.

• In short, candidiasis can disturb the neuroendocrine-immune connection in a variety of ways, with CFS being the undesirable and unpleasant consequence.

It is no coincidence that most CFS sufferers also have numerous symptoms that are typical of candidiasis. Most CFS sufferers have some magnitude of impaired gastrointestinal permeability, implying the presence of leaky gut syndrome (chapters 3 and 4).

Since it is a consistent manifestation of candidiasis, a CFS sufferer is almost certain to be a candidiasis sufferer.

Yet, candidiasis is not always obvious, especially if you do not know what you are looking for and what to treat. Although you must have a high index of suspicion, there are numerous tests that can confirm your suspicions (chapter 17). And knowing what you’re treating is essential to understanding why and how to effectively ensure that you can achieve the best health outcome.

Therefore, if you are a CFS sufferer, or just feel tired, appropriately addressing your candidiasis will give you the greatest chance of getting energized.

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