09/03/2026
LDN is one of the most fascinating tools I’ve used in more than 20 years of integrative medicine—but I’ve learned that it is definitely NOT one-size-fits-all.
Three ways I think about LDN in my practice:
1. IMMUNE MODULATION
The goal isn’t simply to “boost” or suppress the immune system. LDN may help support healthier immune regulation.
2. RESILIENCY
For some patients, LDN appears to be one piece of a larger strategy aimed at helping the body function more effectively in the setting of chronic stress, illness, and inflammation.
3. INFLAMMATION — ESPECIALLY NEUROINFLAMMATION
LDN has proposed anti-inflammatory and neuroimmune effects, which is one reason it continues to interest clinicians caring for patients with chronic pain and complex inflammatory conditions.
But perhaps my biggest teaching point after 20+ years:
The dose matters.
Some highly sensitive patients tolerate doses dramatically lower than the traditional LDN doses commonly discussed. More is not always better.
Educational information only. Not medical advice. Individual response, appropriate dosing, and risks should be discussed with a licensed clinician.
If you want to watch the short video explaining these three points, comment:
“I want the video link”