Shawn Tassone, MD, PhD - America's Holistic Gynecologist

Shawn Tassone, MD, PhD - America's Holistic Gynecologist 2X Board Cert OBGYN + Integrative Medicine | Author of The Hormone Balance Bible - AVAILABLE NOW!
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06/25/2026

Estrogen did not cause your breast cancer — and this is where the conversation gets dangerously misunderstood.

For years, women were told to fear estrogen because of the Women’s Health Initiative — and that fear changed everything.

Women stopped hormone therapy.
Doctors stopped prescribing it.
Menopause symptoms were dismissed.

And an entire generation of women was told to suffer through hot flashes, insomnia, mood changes, vaginal dryness, low libido, joint pain, brain fog, and hormone changes because “estrogen is dangerous.”

Here’s the context that gets lost online: Estrogen does not cause cancer — if it did, every woman with estrogen would get breast cancer.

What estrogen can do is fuel certain existing breast cancer cells that have estrogen receptors — but that is not the same as saying estrogen caused the cancer.

Cancer is multifactorial.
Hormone therapy requires context.
And women deserve better than fear-based medicine, viral misinformation, or one-size-fits-all hormone advice.

Listen to the latest episode of Confessions of a Male Gynecologist to hear me break down the truth about hormone therapy, menopause myths, the Women’s Health Initiative, estrogen fear, bioidentical hormones, testosterone, wellness scams, telehealth hormone clinics, how women can think critically before trusting what they hear online + more!

The goal is not to scare women away from treatment — the goal is to help women understand their options, their risks, their symptoms, and their bodies.

Women don’t need more fear. They need better information.

Save this if you’re navigating perimenopause, menopause, or HRT decisions, share it with a friend + subscribe to the podcast to be notified when a new episode drops each week! 💌

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06/23/2026

One of the biggest mistakes I see people make in healthcare?
Assuming something is beneficial simply because it’s popular.

NAD injections have exploded in the longevity, biohacking, and wellness space.

They’re often marketed for energy, anti-aging, recovery, brain health, and cellular optimization, but a point raised by Daria Hamrah - Facelift-Rhinoplasty deserves more attention.

NAD is not naturally present in plasma, yet we’re increasingly seeing it administered through injections and IVs. Recent research suggests that introducing NAD directly into circulation may trigger an inflammatory response.

Does that mean NAD is “bad”? No.
It means we should be asking better questions.

✅ What does the actual science show?
✅ Is the delivery method biologically appropriate?
✅ Are we discussing the risks as openly as the benefits?
✅ Are people following evidence or simply following trends?

Whether we’re talking about hormones, supplements, NAD, peptides, or the next latest wellness craze, blindly following advice isn’t a strategy.

Not from influencers.
Not from wellness clinics.
Not from social media.

Good medicine requires curiosity from the physician and the patient.
Great healthcare starts when patients ask questions.

💬 Have you tried NAD injections or IV therapy or do you think wellness trends are moving faster than the science?

Share this with a friend diving into longevity, biohacking, or optimizing their health + follow me for more evidence-based conversations about hormones, women’s health, and wellness trends 💌

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06/22/2026

Women deserve to be told what can happen before they start hormone therapy — not after.

If you recently started estrogen, increased estrogen, changed progesterone, missed doses, or switched delivery methods — spotting or bleeding can sometimes happen as the uterine lining responds.

This doesn’t mean you ignore it. The key is knowing what to watch for:
🩸 Is it light spotting or heavy bleeding?
🗓️ How long has it been happening?
🔁 Did it start after a dose change?
💊 Was estrogen increased or progesterone adjusted?
🧾 Are you tracking symptoms, timing, and patterns?

I appreciate Jennifer Roelands, MD, Integrative OB/GYN bringing attention to this because women deserve to know this can happen so they’re not panicking alone at home, but I’ll add one important difference in my approach…

Symptoms tell us how you feel.
Labs help us see what your body is doing.

Labs + symptoms together give us more precision for better dosing, better personalization, and fewer unnecessary side effects — especially when we’re adjusting estrogen and progesterone and trying to reduce side effects like bleeding, breast tenderness, mood changes, or feeling “off.”

Light spotting after a change may be part of the adjustment process, but heavy bleeding, bleeding that lasts too long, or bleeding that feels abnormal for you is worth a call to your provider.

Were you warned that bleeding could happen when starting or changing HRT? 💬

Save this so you know what to track if bleeding or spotting happens after an estrogen or progesterone change, send it to a woman starting hormone therapy + follow me for more honest conversations about women’s health and hormones 💌

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06/20/2026

A great fragrance combo for Father’s Day

Renaissance

It opens with a bright burst of citrus and petitgrain, transitions into a crisp, cool floral-mint heart, and grounds itself in a rich, warm, and earthy woody-musky base

Aventus Absolu

Top notes are Pineapple, Black Currant, Grapefruit, Lemon, Pink Pepper and Bergamot; middle notes are Cardamom, Cinnamon and Ginger; base notes are Vetiver and Patchouli.

06/19/2026

Searching “best progesterone route” online? Here’s what most posts leave out…

Oral progesterone, vaginal progesterone, and re**al progesterone all have different pharmacologic effects.

Oral progesterone undergoes first-pass liver metabolism, which creates metabolites that may support sleep and relaxation.

Vaginal progesterone can provide different absorption patterns and may be preferred in certain clinical situations.

The important takeaway:

There is no universally “best” progesterone route.

There is only the route that best matches your symptoms, goals, and treatment plan.

💬 What questions do you have about progesterone?

Save this post for later, share it with a woman who needs to hear this and follow me for more honest hormone education 💌

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06/16/2026

Male hormones and female hormones both matter, but they do not behave the same way… as you can see 🤪

Men’s hormones: sit calmly in one spot.

Women’s hormones: estrogen, progesterone, testosterone, thyroid, cortisol, insulin, sleep, stress, inflammation, cycle changes, perimenopause, and menopause all try to speak at once.

Men’s hormone patterns tend to be more stable day to day whereas women’s hormones shift across the menstrual cycle, through postpartum, during perimenopause, into menopause, and in response to stress, sleep, blood sugar, thyroid function, inflammation, lifestyle changes etc.

Hormone symptoms need context because a quick “your labs are normal” does not answer the full question. For women especially, we should also look at:
✨ Are you sleeping?
✨ Are you under chronic stress?
✨ Is your thyroid optimized?
✨ Is insulin resistance part of the picture?
✨ Are you in perimenopause or menopause?
✨ Is progesterone low?
✨ Is testosterone being ignored?

Women’s hormones are not dramatic, they’re dynamic — and understanding that difference matters.

💬 Which hormone symptom do you wish your doctor took more seriously?

Save this if you’ve ever felt dismissed after asking your doctor about hormones, share this with a friend who gets it and follow along for more honest women’s health + hormone education 💌

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06/12/2026

Let’s stop pretending every health problem can be solved with a supplement, detox, or functional medicine buzzword.

If your thyroid isn’t making enough thyroid hormone then replacing thyroid hormone makes sense.

That’s literally the job of thyroid medication.

No — it doesn’t “fix” the thyroid, but saying thyroid medication isn’t thyroid medicine because it doesn’t fix the gland is like saying glasses aren’t vision treatment because they don’t regrow your eyeball.

And since he brings up Hashimoto’s…
Yes — autoimmune thyroid disease is more complex.

Inflammation, immune regulation, nutrition, stress, and lifestyle all matter, but many women with Hashimoto’s still need thyroid hormone replacement.

This isn’t either/or.
It’s both/and.

At the end of the day, your treatment plan should be based on your symptoms, your labs, and your individual needs — there is no one-size-fits-all approach to thyroid health.

💬 What’s the most misleading thyroid advice you’ve seen online?

Share this with someone navigating hypothyroidism, Hashimoto’s, or another thyroid related problem + follow me for more hormone education that puts women first 💌

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06/11/2026

POV: you haven’t had an or**sm in over a year… said 4 ways 😂

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