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Coprata Know if your gut is actually thriving. Our Microbiome Activity Tracker (MAT) is a rapid at home test. No shipping required.

Science-based tools and smart devices developed by researchers from Duke University.

You may not know what a menopause coach isYou may soon want 1We are delighted to share a guest post from Renée Balyoz, M...
10/15/2026

You may not know what a menopause coach is
You may soon want 1

We are delighted to share a guest post from Renée Balyoz, M.Ed., a Certified Menopause Coaching Specialist, for Menopause Awareness Month.

Menopause coaching is evidence-based, certified, and specialized in an area where many physicians get limited training. In 1 U.S. survey of medical residents, only 6.8% reported feeling adequately prepared to manage menopause.

Renée's first piece of advice: track your symptoms.

Sleep, hot flashes, anxiety, headaches, joint pain. Concrete data gives your doctor a direction instead of vague complaints.

She lived it!

Soon after a change in her hormone therapy, her Fitbit showed her resting heart rate climbing.

She brought that data to both of her doctors, who ruled out heart issues and adjusted her prescription.

Her post covers what a menopause coach does (and does not do), how coaching supports sleep, nutrition, movement, and stress, and why no woman should go through this transition alone.

www.coprata.com/blog/a-menopause-coachs-take-why-tracking-your-symptoms-changes-the-conversation

Most women with UTIs focus on the bladder. The research suggests they should also be looking at the gut.Up to 90% of com...
10/01/2026

Most women with UTIs focus on the bladder.

The research suggests they should also be looking at the gut.

Up to 90% of community-acquired UTIs are caused by 1 organism.

E. coli.

And it usually does not start in the bladder. It starts in the gut!

For Menopause Awareness Month, we looked at what the research says about the gut-bladder connection.

After menopause, declining estrogen thins the urinary and vaginal tissues and alters local defenses. That is well known. Less discussed is the reservoir. Studies have recovered the same bacterial strains from the stool and urine of people with UTIs.

So why does a microbe that lives quietly in the intestine become a recurrent problem for some women and not others?

It does not appear to be about simply having more E. coli. The more consistent signal is ecological. Gut microbiomes linked with UTIs often have fewer of the bacteria that produce short-chain fatty acids, the compounds that help keep the intestinal environment less welcoming to pathogens.

Then there is the antibiotic question.

Antibiotics are essential for treating UTIs, yet in one study they did not permanently clear the UTI-causing strain from the gut.

None of this proves that improving your gut microbiome prevents UTIs. The evidence is early and the studies are small.

But it is one more reason to care about what your gut microbes are doing, not only which ones are there.

Want the inside scoop? View our blog using the link below!

www.coprata.com/blog/from-gut-to-bladder-the-microbiome-and-utis-in-menopause

Sourdough is a fermented food.It is not a probiotic food.The difference matters more than most people realize."Probiotic...
09/24/2026

Sourdough is a fermented food.
It is not a probiotic food.
The difference matters more than most people realize.

"Probiotic" has a specific scientific meaning:

A live microorganism, present in adequate amounts, with demonstrated health benefits. Baking kills the bacteria and yeast that make sourdough.

Pasteurization does the same to many fermented foods on grocery store shelves. The microbes were there. They are not anymore.

But that is not the whole story.

During fermentation, microbes transform the food. They consume sugars, break down proteins and carbohydrates, and produce compounds called metabolites.

Many of those compounds remain in the food long after the microbes are gone.

The same process occurs in your gut.

When your microbes ferment fiber, they produce short-chain fatty acids like butyrate, which influence your gut lining, immune system, and metabolism.

That is why "who is in your gut?" is only half the question.

The other half is: what are they producing?

Most microbiome tests answer the first question.

Measuring microbial activity (such as f***l pH) begins to answer the second.

The microbes matter. What they produce matters too.

www.coprata.com/blog/fermented-does-not-mean-probiotic-your-gut-actually

October is Menopause Awareness Month!A good moment to focus on a stage of life that deserves more science. Most women wi...
09/17/2026

October is Menopause Awareness Month!
A good moment to focus on a stage of life that deserves more science.
Most women will spend roughly 30 years of their lives after menopause.

Yet of the 10,000+ gut microbiome studies published to date, only a small fraction address menopause and estrogen.

Here are 3 things the research is beginning to show:

1- Postmenopausal women tend to have lower gut microbiome diversity than premenopausal women.

2- The "estrobolome," a group of gut microbes involved in estrogen recycling, may become more significant once ovarian hormone production declines.

3-Some menopause-associated microbial changes are linked to markers such as HDL cholesterol, waist circumference, and blood pressure.

These are associations, not confirmed causes, and many questions remain. But the relationship between gut health and hormones is worth understanding better.

This is the first in a series on women's health and the microbiome.

Read the full article on our blog linked below!

https://www.coprata.com/blog/menopause-and-microbiome-emerging-connection-womens-health

Most people assume ultra-processed food is bad for the brain.The research is more complicated than that.The CDC puts ult...
09/10/2026

Most people assume ultra-processed food is bad for the brain.

The research is more complicated than that.

The CDC puts ultra-processed foods at 53% of the calories American adults consume.

That number alone tends to generate alarm. But the studies behind the headlines tell a messier story.

2 large cohorts, 1 in Brazil and one in the UK, did find links between ultra-processed food intake and faster cognitive decline or higher dementia risk. Those findings are real.

At least 4 others found nothing for total ultra-processed food intake.

A Dutch cohort of 1,371 older adults found no association across any cognitive domain. A US cohort of 4,750 adults found nothing for total intake, only for 2 specific subcategories.

Another study produced the same pattern. A Framingham analysis found an effect only in adults under 68.

When an association does appear, it tends to show up in executive function and global cognition.

Not memory.

The Brazilian study found no memory association at all.

The inconsistency is not surprising once you look at the classification system.

Ultra-processed is a processing category, not an ingredient list.

Industrial whole-grain bread and a snack cake land in the same bucket.

Averaging them into a single number was always going to produce noisy results.

The more legible story is mechanistic.

Industrial processing strips out the fermentable fiber that gut bacteria depend on, and it adds compounds like emulsifiers that, in mouse studies and at least one small human feeding trial, disrupt the microbial community and reduce short-chain fatty acid output.

That part is measurable. Less fermentable fiber means less fermentation, fewer short-chain fatty acids, and less acid in the colon.

The gut connection is well documented.

The step from gut to brain is still inference.

Anyone framing it as settled science is ahead of the evidence.

Want to dive even deeper? Check out our blog for more insight and data!

www.coprata.com/blog/ultra-processed-food-the-brain-what-the-research-shows

Measuring short-chain fatty acids accurately requires a mass spectrometerNot a home kit, not a strip. It requires gas or...
09/03/2026

Measuring short-chain fatty acids accurately requires a mass spectrometer
Not a home kit, not a strip.

It requires gas or liquid chromatography paired with mass spectrometry, solvent extraction, derivatization, and internal standards to correct for matrix effects.

This is why almost everything we know about SCFAs comes from research settings.

Why do individuals tracking their own gut health have almost no access to that data?

There is, however, a pattern worth paying attention to.

Across 11 human studies, higher total f***l SCFA concentrations were consistently associated with lower stool pH.

In the 5 studies that included pH data, both total SCFA and the percentage of butyrate increased as pH decreased.

Oliver and colleagues stated it directly in 2024: f***l pH can serve as a proxy for SCFA activity.

2 things to keep in mind:

1- Stool pH is indirect. It reflects absorption, transit time, diet, and fermentation activity.

2- More acidic is not automatically better.

Liu and colleagues make the case that SCFA levels exist in a dynamic balance, where both extremes carry risk. There is a healthy range, not a finish line.

That proxy relationship is what the Microbiome Activity Tracker is built on:

Lab-grade insight into fermentation activity, without the lab.

www.coprata.com/blog/how-scfas-are-actually-measured-why-stool-ph-is-the-practical-shortcut

Sleep doesn't just affect your brain.It affects your gut too.The relationship runs both ways.Poor sleep can alter the co...
08/27/2026

Sleep doesn't just affect your brain.
It affects your gut too.
The relationship runs both ways.

Poor sleep can alter the composition and activity of your gut microbiome, while your gut bacteria produce compounds that may influence sleep quality.

Certain bacteria are involved in pathways tied to serotonin and GABA, 2 neurotransmitters that regulate relaxation and sleep.

Your microbiome also operates on its own 24-hour rhythm. Irregular sleep, late-night eating, and shift work can disrupt that rhythm, much like jet lag disrupts yours.

Short-chain fatty acids offer a clear example.
These are compounds your gut bacteria produce when fermenting fiber.

In a 2024 study, women with longer sleep duration had higher levels of these beneficial compounds in their stool. Suggesting that sleep may shape your gut's output as much as your diet does.

2 practical starting points:

1- Power down 30 to 60 minutes before bed.

Screens delay sleep more than most people realize, largely because of the time they consume, not just the light they emit.

2- Try a weighted blanket.

The gentle pressure is thought to activate the body's rest-and-digest response. Research on insomnia is still developing, but several studies point to real benefits for anxiety and sleep onset.

Shoutout to Julia Darcy for the idea behind the weighted blanket angle.

Good sleep belongs right alongside diet, exercise, and stress management as part of a gut-healthy routine.

https://www.coprata.com/blog/why-sleep-deserves-place-in-your-gut-health

You don't need the $2 packet in your water. You need to drink more water.Electrolyte powders have quietly become a welln...
08/13/2026

You don't need the $2 packet in your water.
You need to drink more water.

Electrolyte powders have quietly become a wellness default.

Gym bags, TikTok, the checkout line at Whole Foods.

The pitch is simple:
Better hydration, more energy, faster recovery.
The problem is that most people reaching for them don't actually have an electrolyte problem. They have a "I forgot to drink water today" problem.

Here's what the research actually shows:

Sodium, potassium, and the other minerals in those packets are already covered through a normal diet.

Your body isn't short on electrolytes. It's short on consistent fluid intake, and that's a different fix entirely.

Underhydration itself is worth taking seriously.

Studies following people over 6 to 15 years have linked chronically low fluid intake with higher rates of type 2 diabetes, coronary artery disease, heart failure, and reduced kidney function.

That's not a reason to add electrolytes. It's a reason to drink more water.

So when do electrolytes actually matter?

A narrower window than the marketing suggests:

- Intense exercise lasting an hour or more
- Multiple hours of outdoor activity
- Exercise in serious heat or humidity

Outside of those conditions, plain water covers it and skips the added sugar that comes with most powdered mixes.

One more thing worth knowing:

Your thirst signal lags behind your actual hydration need.

By the time you feel thirsty, you're already behind. A simple fix is building water into a routine you already have, like pairing your morning coffee with a full glass of water.

The takeaway isn't that electrolytes are a scam. It's that they're solving a problem most people don't have, while the actual problem of not drinking enough water in the first place goes unaddressed.

Full breakdown in our blog below:
www.coprata.com/blog/do-you-really-need-electrolytes-or-salty-water

It is incredibly rewarding to see something we invented at Coprata being used again and again—thousands of times now—to ...
08/11/2026

It is incredibly rewarding to see something we invented at Coprata being used again and again—thousands of times now—to make this kind of microbiome research possible.

This is exactly the kind of work we hoped our technology would enable: studying the same people over time, in their everyday lives, to uncover patterns that would otherwise be very difficult to see. Proud to be part of the FIBER-IMPACT collaboration with Nestlé Health Science and our research partners.

Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.

August is National Wellness Month!We talk a lot here about nutrition and gut health. This month, we're turning to the ot...
08/06/2026

August is National Wellness Month!
We talk a lot here about nutrition and gut health.
This month, we're turning to the other pillars of wellness, starting with movement.

Most of us sit for 9 to 11 hours a day!

More than half our waking hours. Sitting is not "the new smoking," that comparison does not hold up scientifically. But it is not without consequence either.

When leg muscles stay inactive for hours, they stop clearing glucose and fat from the bloodstream the way they do during movement. Blood flow to the legs slows. Over years, that accumulates.

The answer is not necessarily more time at the gym.

A 2026 study of over 11,000 adults found that five-minute movement breaks.

Taken every 30, 60, or 120 minutes reduced fatigue and improved mood without affecting work performance.

Hourly breaks offered the most practical benefit.

No equipment needed. A walk to refill your water bottle counts.

Check out what you can do for August in our blog!
www.coprata.com/blog/sitting-all-day-5-minute-habit-help-you-live-better

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