09/24/2026
Menopause is also a cardiometabolic transition.
Changes during menopause reach far beyond hot flashes. Declining estrogen may be accompanied by changes in abdominal fat distribution, insulin sensitivity, cholesterol, blood pressure, bone health and muscle maintenance.
Recent research continues to emphasize that metabolic syndrome deserves particular attention after menopause. One cohort study found that metabolic syndrome was associated with increased cardiovascular risk in postmenopausal women, with especially strong associations among women with elevated fasting glucose or earlier menopause.
This is why a thoughtful menopause evaluation may include more than hormone levels.
We may also consider:
• Blood pressure and waist circumference
• Fasting glucose and fasting insulin
• Triglycerides, HDL, LDL and ApoB, Lp (a)
• Skeletal muscle mass and grip strength
• Sleep and stress regulation
• Individual risks and benefits of hormone therapy
Menopause is an important time for women to consider the opportunities for prevention.