06/17/2026
Many people assume that if they feel anxious, shaky, sweaty, or have a racing heart after starting T3, the medication must be the problem.
But sometimes the real issue is insulin resistance.
T3 increases the rate at which your cells use energy. If insulin resistance is present, blood sugar can rise and fall more dramatically. When blood sugar drops quickly, your body responds with stress hormones like cortisol and adrenaline.
That adrenaline surge can feel a lot like "T3 intolerance":
• Shakiness
• Irritability
• Anxiety
• Sweating
• Heart palpitations
• Even panic-like symptoms
The irony is that the T3 may not be causing the problem at all. It may simply be revealing an underlying metabolic issue that was already there.
This is one reason why nutrition, sleep, stress management, exercise intensity, and sometimes insulin resistance treatment can be just as important as thyroid medication itself.
🎧 From Beyond the Thyroid – Episode 46: When T3 Doesn't Work — How to Dose Thyroid Medication Correctly (Part 2) https://youtu.be/JS0KzdkwjTs
My CORE5 lab guide explains what your TSH misses and what to order instead. Comment CORE5 and I'll send it.