07/21/2026
Sample IVIG orders. IVIG is typically dosed 0.4-0.8 g/kg for immune deficiency, and for PANS/PANDAS/other neuroimmune disorders, "high dose" is typically required. High dose is 1.5-2 g/kg. Begin infusion at 0.8 mg/kg/min.
30 minutes after beginning the infusion, if no adverse reaction occurs, increase infusion to 1.7 mg/kg/min.
Infuse over 7 hours (for high dose; shorter duration for regular dosing)
and continue at this rate until remaining volume is infused. This may take two days for high dose. Patients receive 500-1000mL of IV fluids prior to infusion, as well as acetaminophen and diphenhydramine. Sometimes we add a dose of oral prednisone prior to infusion.