The New England Journal of Medicine

The New England Journal of Medicine The New England Journal of Medicine (NEJM.org) is the world's leading medical journal and website.

In a new NEJM Voices blog post, Dr. Theodore Iwashyna reminds leaders to break bread with your entire multidisciplinary ...
08/30/2026

In a new NEJM Voices blog post, Dr. Theodore Iwashyna reminds leaders to break bread with your entire multidisciplinary team to show them you appreciate them.

08/30/2026

A new Video in Clinical Medicine demonstrates how to insert a catheter for emergency peritoneal dialysis in adults with a technique created specifically for environments that may have limited access to resources.

In a new NEJM Voices blog post, Dr. Michelle Kittleson discusses the CARDIO-TTRansform trial results, which offer a less...
08/29/2026

In a new NEJM Voices blog post, Dr. Michelle Kittleson discusses the CARDIO-TTRansform trial results, which offer a lesson in looking beyond topline results to understand what the findings really mean for patient care.

A 33-year-old man with systemic lupus erythematosus presented with a 1-week history of pruritic, burning plaques. Examin...
08/29/2026

A 33-year-old man with systemic lupus erythematosus presented with a 1-week history of pruritic, burning plaques. Examination showed pink, edematous plaques on the hands, elbows, knees, and feet. Laboratory testing showed elevated antinuclear and anti–double-stranded DNA antibody levels and low complement levels. Skin biopsy showed leukocytoclastic vasculitis. Treatment with oral and topical glucocorticoids was started. One week later, the lesions evolved into fixed, urticarial, annular, and targetoid plaques with rims of purpura on the thighs, chest, abdomen, and back. What is the most likely diagnosis?

In a new NEJM Voices blog post, Dr. Kemi Doll shares three important steps in training yourself to use your voice in aca...
08/28/2026

In a new NEJM Voices blog post, Dr. Kemi Doll shares three important steps in training yourself to use your voice in academic medicine.

A woman presented with a 2-year history of pain, swelling, and stiffness in the wrists and fingers. Deformities were not...
08/28/2026

A woman presented with a 2-year history of pain, swelling, and stiffness in the wrists and fingers. Deformities were noted in her fingers and thumbs. When the hands were clenched into fists, the deformities resolved, as shown in a video.

Visual artist Ryan Montoya, MD, a family medicine physician, presents his debut comic with NEJM Voices.
08/27/2026

Visual artist Ryan Montoya, MD, a family medicine physician, presents his debut comic with NEJM Voices.

Case Record of the Massachusetts General Hospital: A 74-year-old man with myasthenia gravis was evaluated for dyspnea, p...
08/26/2026

Case Record of the Massachusetts General Hospital: A 74-year-old man with myasthenia gravis was evaluated for dyspnea, proximal muscle weakness, hypoxemia, and a painful tongue lesion. Medications included prednisone and mycophenolate mofetil. A diagnosis was made.

An 82-year-old man was brought to the ED after being “found down.” One week earlier, he had returned from a 1-month visi...
08/25/2026

An 82-year-old man was brought to the ED after being “found down.” One week earlier, he had returned from a 1-month visit to Chad. A peripheral-blood smear showed ring-form trophozoites within erythrocytes.

A new review summarizes the pathogenesis and treatment of myeloproliferative neoplasms, highlighting the role of driver ...
08/24/2026

A new review summarizes the pathogenesis and treatment of myeloproliferative neoplasms, highlighting the role of driver mutations, inflammation, and emerging targeted therapies that may achieve durable disease modification.

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