NEJM Catalyst

NEJM Catalyst Practical innovations in health care delivery:

Ideas, solutions, and case studies to improve patient care and drive value in health organizations.

Health care delivery is undergoing a major transformation around quality, cost, and access. NEJM Catalyst brings health care executives, clinician leaders, and clinicians together to share innovative ideas and practical applications for enhancing the value of health care delivery. NEJM Catalyst brings insightful articles and real-life examples from a network of top thought leaders, experts and adv

isors to provide:

Practical innovations in health care delivery;

Impeccable quality and impact;

Active contributions from renowned authorities, thought-leaders, and advisors;

Independent and impartial curation; and

An exchange of ideas among executives and clinicians. NEJM Catalyst is produced by NEJM Group, a division of the Massachusetts Medical Society, located in Waltham, Massachusetts.

The implementation of and ongoing improvements to the primary care virtual shared medical appointment model at Massachus...
05/30/2026

The implementation of and ongoing improvements to the primary care virtual shared medical appointment model at Massachusetts General Hospital led to program growth and is associated with improved health outcomes, including blood pressure control — without any significant increase in medications — through its four-part hypertension series: https://nej.md/4ulab4l

The Yale School of Medicine Department of Emergency Medicine developed a comprehensive cross-domain approach to emergenc...
05/29/2026

The Yale School of Medicine Department of Emergency Medicine developed a comprehensive cross-domain approach to emergency care, from prehospital care to emergency department care to postdischarge planning, using an adaptive framework with emphasis on both Safety I and Safety II principles: https://nej.md/4nWH9FT

A survey of the NEJM Catalyst Insights Council finds substantial doubt, especially in the United States, that health car...
05/28/2026

A survey of the NEJM Catalyst Insights Council finds substantial doubt, especially in the United States, that health care provider organizations can rely on federal agencies for accurate information about public health concerns: https://nej.md/4ula2Ol

The June 2026 issue of NEJM Catalyst Innovations in Care Delivery includes research reports, articles, case studies, and...
05/27/2026

The June 2026 issue of NEJM Catalyst Innovations in Care Delivery includes research reports, articles, case studies, and commentaries on public health, high-quality emergency care, deterioration response, chronic disease care, obesity care, cervical cancer screening, missed patient appointments, AI deployment, and patient storytelling: https://nej.md/3PM2rZY

Many strategic plans falter because they fail to connect with the individuals responsible for bringing them to life. Mem...
05/27/2026

Many strategic plans falter because they fail to connect with the individuals responsible for bringing them to life. Memorial Sloan Kettering Cancer Center bridged the gap between strategy and ex*****on using the age-old human practice of storytelling. By harnessing the emotional power and connective force of narrative, Memorial Sloan Kettering Cancer Center reimagined its approach to strategic planning — not as a static document, but as a shared journey: https://t.co/ek9C6iu0Kf

Call for papers (deadline June 1): Assessing Implementation and Impact of the 4Ms Framework to Advance Age-Friendly Heal...
05/26/2026

Call for papers (deadline June 1): Assessing Implementation and Impact of the 4Ms Framework to Advance Age-Friendly Health Systems — Special Theme Issue https://nej.md/4kNTpXw

Unrecognized physiologic deterioration is a persistent challenge across health care systems, resulting in missed opportu...
05/26/2026

Unrecognized physiologic deterioration is a persistent challenge across health care systems, resulting in missed opportunities for early intervention and reduced inpatient mortality. Early detection and structured response protocols may improve clinical outcomes.

In this retrospective propensity-matched cohort study, the authors evaluate the effectiveness of the Discover, Evaluate, Triage, Evaluate, and Respond (DETER) program on clinical outcomes among adult inpatients across a large, multihospital health system.

Of 99,558 eligible admissions, 39,703 intervention cases were matched 1:1 to control cases. In-hospital mortality was 1.7% in the intervention group and 2.9% in the control group, representing a 41% relative reduction. The average hospital length of stay was 6.7 days in the intervention group and 7.1 days in the control group. The rates of hospice discharge, intensive care unit transfers, and upgrades to higher levels of care were decreased in the intervention group. Rapid response team activations increased from 6.7% in the control group to 10.2% in the intervention group (P

Virtually all cervical cancers are caused by high-risk human papillomaviruses (HPVs), which can be accurately detected u...
05/26/2026

Virtually all cervical cancers are caused by high-risk human papillomaviruses (HPVs), which can be accurately detected using deoxyribonucleic acid (DNA) testing from cervical or vaginal samples. Patient vaginal HPV self-collection (HPV self-collect) presents new opportunities to expand access to cervical cancer screening, improve uptake, and reach underrepresented populations.

An integrated health system in Washington State implemented a mail- and clinic-based HPV self-collect program. Researchers partnered with health system leaders and clinicians to evaluate program implementation. This report describes the program, evaluation methods, challenges encountered, and proposed solutions.

Primary outcomes observed after program implementation included increases in cervical cancer screening uptake, reduction in pelvic examination utilization, and generally positive clinician response based on interviews and site visits.

Key lessons included the need for clear documentation and quality assurance procedures to identify eligible individuals and distribute mailed HPV self-collect kits, as well as standardized workflows for in-clinic distribution.

Site visits and interviews revealed that clinicians generally appreciated the program — some noted that it changed their practice by reducing time spent on pelvic examinations, allowing more time to address patients’ other health issues — and reported that patients found it acceptable or preferable.

However, concerns were raised by clinicians and by patients to their clinicians about screening quality, and clinicians had knowledge gaps regarding the accuracy of both primary HPV screening and patient-collected samples.

Iterative sharing of evaluation goals and findings between researchers and health system leaders led to program improvements and identified further opportunities for strengthening implementation.

HPV self-collect provides an opportunity to efficiently screen more people for cervical cancer and potentially increase primary care access: https://nej.md/4fwFlRr

Postdeployment monitoring of artificial intelligence (AI) systems in health care is essential to ensure their safety, qu...
05/25/2026

Postdeployment monitoring of artificial intelligence (AI) systems in health care is essential to ensure their safety, quality, and sustained benefit — and to support governance decisions about which systems to update, modify, or decommission. Motivated by these needs, the authors developed a framework for monitoring deployed AI systems organized around three complementary principles: system integrity, performance, and impact.

System integrity monitoring focuses on maximizing system uptime, detecting runtime errors, and identifying when changes to the surrounding information technology ecosystem have unintended effects. Performance monitoring focuses on maintaining accurate and equitable system behavior in the face of changing health care practices (and thus input data) over time. Impact monitoring assesses whether a deployed system continues to have value in the form of benefit to clinicians, staff, and patients.

Drawing on examples of deployed AI systems at their academic medical center, the authors provide practical guidance for creating monitoring plans based on these principles that specify which metrics to measure and at what cadence, who is responsible for acting when metrics change, and what concrete follow-up actions should be taken — for both traditional and generative AI.

They also discuss challenges in implementing this framework, including the effort of monitoring for health systems with limited resources, and the difficulty of incorporating data-driven monitoring practices into complex organizations where conflicting priorities and definitions of success often coexist.

This framework offers a starting point for health systems seeking to ensure that AI deployments remain safe and effective over time: https://nej.md/3PzjPB9

Address

860 Winter Street
Waltham, MA
02451

Opening Hours

Monday 8am - 4pm
Tuesday 8am - 4pm
Wednesday 8am - 4pm
Thursday 8am - 4pm
Friday 8am - 4pm

Alerts

Be the first to know and let us send you an email when NEJM Catalyst posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Contact The Business

Send a message to NEJM Catalyst:

Share