Dysautonomia Clinic

08/29/2026

🔥 The very first Delphi consensus paper on POTS and is published! Dr. Blitshteyn is honored to serve as a co-Chair on this clinician-led, Multidisciplinary International POTS and Dysautonomia Expert Panel! The goal of this initiative is to improve clinical care of patients with POTS and dysautonomia and to provide clinician education. 🧠

Key points:
✔️POTS represents a subset of patients with dysautonomia.
✔️Patients who do not fulfill the diagnostic criteria for POTS may have dysautonomia that is not POTS (non-POTS dysautonomia).
✔️Both POTS and dysautonomia need to be diagnosed and treated correctly - not with psychotherapy or antidepressants.
✔️Patients with POTS and patients with non-POTS dysautonomia need to have access to care, work and school accommodations and disability benefits if necessary.
✔️Therapeutic trials, multidisciplinary patient care and physician education/training are needed to advance the field and improve the lives of patients with POTS and patients with non-POTS dysautonomia.

Read full (pre-proof) paper here: 👇

Current diagnostic criteria for postural orthostatic tachycardia syndrome (POTS) require history of orthostatic intolerance and heart rate elevation of ≥30 bpm in adults or ≥40 bpm in adolescents during a 10-minute standing or a tilt table test. Many patients with orthostatic intolerance experie...

07/24/2026

💥 Dysautonomia Clinic Research Team is plotting the next several studies! Some of our amazing researchers met yesterday to discuss them. 🧠

07/16/2026

🧠 Dr. Blitshteyn's new paper discusses evaluation of orthostatic dizziness in older adults. Neurologists should be trained to diagnose and treat patients with autonomic dysfunction.
https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2026.1803374/full

06/24/2026

Are you taking duloxetine (generic for Cymbalta)? There is an FDA recall of this drug. Please check with your pharmacist.

Antidepressant recalled over impurity linked to potential cancer risk.

06/19/2026

💥 Drs. Blitshteyn and Trimble and our incoming Jacobs School of Medicine & Biomedical Sciences - University at Buffalo medical student, who is joining our research team for her neurology research elective, enjoyed the beautiful weather and lunch outside while discussing our multiple ongoing research studies. 🧠

05/24/2026

A new documentary,"The Crash," is trending on Netflix. POTS was used by Mackenzie's defense team to claim that she allegedly passed out behind the wheel, which caused the crash. Dr. Blitshteyn was invited on Fox News Houston Morning Show yesterday to explain POTS during their live show.
https://www.netflix.com/tudum/articles/the-crash-where-is-mackenzie-shirilla-now

05/14/2026

🔥 Just published: new paper from Dysautonomia Clinic Research Team on abnormal ge***al symptoms in patients with dysautonomia and comorbidities.
✔️ 10 patients with autonomic disorders (6 with POTS) and comorbidities describing abnormal ge***al arousal and sensory symptoms
✔️ 8 of 10 patients had positive autoimmune or inflammatory markers, the most common being positive ANA
✔️ Patients' ge***al symptoms improved by targeted therapies for autonomic dysfunction and autoimmunity, including IVIG. One patient no longer needed Vi**ra when given anhigh dose of IVIG.
✔️ Findings suggest that abnormal ge***al sensory symptoms, erectile dysfunction, decreased libido or ge***al hyperarousal could stem from autonomic dysfunction, autoimmunity and small fiber neuropathy.

Read full paper here: 👇
https://academic.oup.com/jsm/article/23/6/qdag138/8677942

05/04/2026

🧠 New paper by Dr. Blitshteyn and colleagues criticizing an unfounded promotion of brain-body therapy for treatment of POTS. Too often doctors jump to psychotherapies for treatment of complex chronic disorders, but it's important to emphasize that there is no scientific evidence that brain-body therapy, cognitive-behavioral therapy or other forms of psychotherapy are effective for patients with POTS.

Read full paper here: 👇
https://link.springer.com/epdf/10.1007/s10286-026-01217-0?sharing_token=whrBqWc8MggzcwIKOPG82ve4RwlQNchNByi7wbcMAY7h_fr63cFl_s5L5VUGum8mlMWgzS96gLAv6i-eevLjjHtkA2TQs1w9UJZ4ZADi8BhRKynBYzG85-eznxp1bxOLlc8fn07BOCdssinZGuWUkehtu_Vy2aaxJQirX2bM-7s%3D

04/17/2026

✍️ Read Dr. Blitshteyn's letter, "Living alongside your chronic illness: No two patients are alike," in response to an opinion published in the British Medical Journal. She discusses the issues of resilience and ableism in chronic illness. 🩺

https://www.bmj.com/content/393/bmj.s674/rapid-responses

04/15/2026

Thank you for sharing our paper, ApresJ20 - Association Covid Long France!

🧵🧠🧬Une nouvelle revue (2026) propose un changement majeur de paradigme :
, et pourraient être des maladies neuro-immunes

Ces trois pathologies ne sont pas séparées.
Elles partagent une physiopathologie complexe, multi-systémique et imbriquée.

👉En réalité, elles se recoupent largement.

Les chercheurs identifient plusieurs mécanismes communs majeurs :

•Dysfonction du système nerveux autonome
•Dérégulation immunitaire
•Auto-immunité
•Neuroinflammation
•Hypoperfusion cérébrale
•Dysfonction mitochondriale

👉Une signature clairement neuro-immunitaire.

Le POTS et l’EM font partie des phénotypes les plus fréquents du Covid Long
➡️Responsables d’un handicap important et durable

Un point clé :
👉La dysautonomie est centrale

Elle peut toucher :
❤️Cœur
🧠Cognition
🌡️Régulation thermique
🍽️Digestion

➡️expliquant la diversité des symptômes.

Dans le , la dysfonction autonome serait présente chez environ 70% des patients

👉Ce n’est pas marginal. C’est un mécanisme central.

Côté cerveau 🧠
Des études suggèrent :

•neuroinflammation
•atteinte du tronc cérébral
•perturbation des circuits neuro-végétatifs

👉Cohérent avec les symptômes neurologiques.

Pour l’ :
👉anomalies neuro-immunes et inflammatoires
👉altérations cérébrales (insula, thalamus, système limbique)

➡️renforçant l’idée d’une maladie organique.

🗣️Le message fort des auteurs :

👉Ces maladies doivent être intégrées à la neuro-immunologie
(comme la sclérose en plaques, etc.)

❓Pourquoi c’est crucial ?

•Meilleure reconnaissance médicale
•Formation des médecins
•Développement de traitements ciblés
•Parcours de soins adaptés

👉Un enjeu majeur de santé publique.

Cela implique aussi un changement de regard :

❌Fin des approches réductrices ou psychologisantes
✅Reconnaissance de maladies biologiques complexes

🧭Conclusion :

Le Covid Long, l’EM et le POTS ne sont pas des syndromes isolés.
👉Ils appartiennent probablement à un continuum neuro-immun.

➡️Un tournant pour la recherche… et pour les patients.

Millions Missing France

🔗 https://www.dovepress.com/postural-orthostatic-tachycardia-syndrome-myalgic-encephalomyelitischr-peer-reviewed-fulltext-article-ITT