Fillmed SA

01/06/2026

By reactivating skin cells, NCTF® 135 HA helps restart the skin’s natural biological functions.

This injectable skin-rejuvenation solution works directly within the dermis, where the ageing process begins.

Its formula specifically targets fibroblasts — the cells responsible for producing collagen and elastin.

The observed results are significant:

+148%(1) fibroblast stimulation
+256%(1) collagen production

This action helps strengthen the skin’s structure, improve firmness, and restore the skin’s ability to better withstand the effects of time. ✨



(1) Polycomponent mesotherapy formulations for the treatment of skin ageing and improvement of skin quality, Sergey Prikhnenko, Clinical, Cosmetic and Investigational Dermatology 2015:8 151–157. Results obtained using NCTF® powder.

29/05/2026

What differences can you see when adding NCTF® 135 HA to your laser treatment?
🎀 Faster post-treatment recovery
✨ Greater skin quality improvements, such as +42% radiance
🫶 Higher patient satisfaction

Combination is the new standard for more personalised results.

For great skin quality, just add NCTF® 135 HA.



Study conducted as a comparative split-face pilot study.

[1] on file. Mahdavinia M, et al. Polyrevitalising solution improves the effects of CO2 fractional laser: A comparative split face pilot study.

Laboratoires FILLMED does not endorse, promote or assume liability for any off-label use of its products. NCTF® 135 HA is an injectable medical device. Ask your doctor for advice. If any adverse event occurs, please inform your doctor. Vigilance contact (notification of an adverse event): [email protected]

27/05/2026

94% of doctors* combine NCTF® 135 HA with other aesthetic treatments to boost results and patient satisfaction. 👨‍⚕️

👉 NCTF® 135 HA improves skin quality, deeply hydrates, prepares the skin to receive other treatments, and enhances overall results.

It is the ideal product for a natural, tailored treatment protocol.

NCTF® 135 HA is an anti-ageing injectable product indicated for filling superficial wrinkles, revitalising and intensely hydrating tired or dull skin, and improving skin evenness and radiance. It also helps improve density, thickness, and elasticity in mature or lax skin. Injectable Class III medical device (CE 0477).

Possible side effects of NCTF® 135 HA: systemic allergic reactions (angioedema, allergic reaction, itching sensation, skin rash, chills, fever), local inflammatory reactions (redness, swelling, burning sensation, nodules, granulomas, pain, skin inflammation), local allergic reactions (itching), and infection (abscess, herpes).

Please refer to the product instructions for more information. Products are not included on the list referred to in Article L. 165-1 of the French Social Security Code. Vigilance contact (to report adverse effects): [email protected]

*Internal data

Internal reference: MIX-135-07-2025
ANSM reference: 25-09-FILLMED-GP-001

26/05/2026

Rejuvenating the décolleté is possible.✨

A fragile and often neglected area, the décolleté deserves special attention.
With NCTF® 135 HA, restore all its beauty and youthful appearance.

📉 32% fewer wrinkles after only 3 sessions (1)

NCTF® 135 HA is an anti-ageing injectable product indicated for the correction of superficial wrinkles, for intense revitalisation and hydration of tired or dull skin, and to improve the skin’s evenness and radiance. It also helps improve density, thickness, and elasticity in mature or sagging skin. Injectable class III medical device (CE 0477).

Undesirable effects of NCTF® 135 HA: A systemic allergic reaction (Quincke’s oedema, allergic reaction, itching sensation, skin rash, chills, fever), local inflammatory reaction (redness, swelling, burning sensation, nodule, granuloma, pain, skin inflammation), local allergic reaction (itching), and infection (abscess, herpes). Please consult the product instructions for more information. Products not included on the list mentioned in article L.165-1 of the French Social Security Code. Vigilance contact (reporting an adverse effect): [email protected].

(1) Comparative clinical trial on the face and neck comparing Nanosoft® and the classic needle for the anti-ageing effects of NCTF® 135 HA on 40 healthy volunteers, 2019. Randomised, controlled, monocentric, prospective study. 3 sessions spaced 21 days apart on the face and neck. Clinical score + instrumental measurements. (H**E 3 study)

Internal reference: MIX-135-07-2025
ANSM reference: 25-09-FILLMED-GP-001

20/05/2026

Explore the full potential of NCTF® 135 HA

Master the strategic injection areas of NCTF® 135 HA to maximize results. 💉💕

These targeted areas help to:

✨ Revitalize the skin
✨ Refine skin texture
✨ Reveal natural radiance

NCTF® 135 HA is an anti-ageing injectable product indicated for the correction of superficial wrinkles, for the revitalisation and intense hydration of tired or dull skin, and to improve skin tone evenness and radiance. It also promotes redensification, thickness, and elasticity in mature or sagging skin. Class III injectable medical device (CE 0477).

Possible side effects of NCTF® 135 HA:
A systemic allergic reaction (Quincke’s oedema, allergic reaction, itching sensation, skin rash, chills, fever), local inflammatory reaction (redness, swelling, burning sensation, nodule, granuloma, pain, skin inflammation), local allergic reaction (itching), and infection (abscess, herpes).

Please consult the product instructions for more information. Products not included on the list mentioned in Article L.165-1 of the French Social Security Code. Vigilance contact (to report an adverse effect): [email protected]

Internal reference: MIX-135-07-2025
ANSM reference: 25-09-FILLMED-GP-001

Email: [email protected] or call +27 12 548 0725 for FILLMED South Africa enquiries.

18/05/2026

Why use NCTF® 135 HA with laser treatments?

💬 “When I have patients coming for laser treatments, I like to prepare the skin with NCTF® 135 HA. It’s the product that is the most studied product for so many years.”
💬 “We deliver all the nutrients, make sure it’s got a lot of hydration, because then you have a better laser outcome and you start the whole wound healing process with healthy cells.”

For great skin quality, just add NCTF® 135 HA.

Laboratoires FILLMED does not endorse, promote, or assume liability for any off-label use of its products. NCTF® 135 HA is an injectable medical device. Ask your doctor for advice. If any adverse event occurs, please inform your doctor. Vigilance contact (notification of an adverse event): [email protected]

16/05/2026

NCTF® 135 HA: Your aesthetic essential 💎

Whether starting your aesthetic journey or enhancing ongoing results, NCTF® 135 HA fits into every aesthetic journey
🔹A smart foundation to prepare and maintain results
🔹The potentiator to enhance the effect of every other aesthetic procedure

🎯 The versatile synergistic partner to every doctor with its unique action.

NCTF® 135 HA is an injectable medical device. Ask your doctor for advice. If any adverse event occurs, please inform your doctor. Vigilance contact (notification of an adverse event): [email protected]

Email: [email protected] or call +27 12 548 0725 for FILLMED South Africa enquiries.

13/05/2026

12/05/2026

NCTF® 135 HA embodies the perfect alliance between science, precision and performance, in a format that is as minimalist as it is powerful. 🔬

Formulated with 60 essential ingredients, this regenerative product was designed to provide the skin with an optimal environment that promotes cellular activation.

In this bottle:
• high biocompatibility
• 45 years of scientific expertise
• seamless integration into aesthetic protocols
• the promise of visible, natural and progressive results

An approach where science elevates the art of skincare… down to the finest detail.



Internal reference: MIX-016-02-2026

NCTF® 135 HA is an anti-ageing injectable product indicated for the correction of superficial wrinkles, for the revitalisation and intense hydration of tired or dull skin, and to improve the skin’s evenness and radiance. It also promotes redensification, thickness and elasticity in mature or lax skin.

Class III injectable medical device (CE 0477).

Undesirable effects of NCTF® 135 HA:
A systemic allergic reaction (Quincke’s oedema, allergic reaction, itching sensation, skin rash, chills, fever), local inflammatory reaction (redness, swelling, burning sensation, nodule, granuloma, pain, skin inflammation), local allergic reaction (itching) and infection (abscess, herpes).

These medical devices are regulated healthcare products bearing the CE marking under this regulation. Treatment with filler products may require several touch-ups over time to achieve the desired correction. The use of these products requires intervention by a healthcare professional; consult your doctor for advice.

Vigilance contact (reporting an adverse effect): [email protected].

Email: [email protected] or call +27 12 548 0725 for FILLMED South Africa enquiries.

11/05/2026

How do you use NCTF® 135 HA for scars?
💬 “We already have the studies, and we already know by science that NCTF® 135 HA can prepare the skin before surgery and can be a solution in case you need a better-looking scar.”

For great skin quality, just add NCTF® 135 HA.

Laboratoires FILLMED does not endorse, promote, or assume liability for any off-label use of its products. NCTF® 135 HA is an injectable medical device. Ask your doctor for advice. If any adverse event occurs, please inform your doctor. Vigilance contact (notification of an adverse event): [email protected]

Email: [email protected] or call +27 12 548 0725 for FILLMED South Africa enquiries.