08/27/2026
Epitalon (AEDG) is a synthetic tetrapeptide derived from the pineal gland that has been studied for over 25 years across in vitro, in vivo, and clinical research. Current research areas include geroprotective and anti-aging effects through telomerase activation and telomere elongation, antioxidant and antimutagenic properties, neuroendocrine regulation including direct influence on melatonin synthesis, neuroprotective effects in neurodegenerative models, potential anti-tumor activity demonstrated in multiple animal models, and circadian rhythm regulation confirmed in a clinical trial involving 75 women. Despite promising findings, its precise mechanism of action remains unclear and large-scale clinical trials are still needed.
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