BMJ Best Practice

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🔍 What’s the diagnosis?A 36-year-old woman with Fitzpatrick type I skin presents with an enlarging pigmented lesion on t...
03/06/2026

🔍 What’s the diagnosis?

A 36-year-old woman with Fitzpatrick type I skin presents with an enlarging pigmented lesion on the posterior calf.

She reports previous sunburns and regular tanning bed use.

On examination, the lesion measures 1 cm and shows:

▪️ Asymmetry
▪️ Colour variegation
▪️ Irregular borders

🩺 What’s your diagnosis?

Explore the BMJ Best Practice topic here 👉 https://bestpractice.bmj.com/topics/en-gb/268

🚨 New treatment options for uncomplicated urogenital gonorrhoea: the FDA has approved zoliflodacin (Nuzolvence) and gepo...
01/06/2026

🚨 New treatment options for uncomplicated urogenital gonorrhoea: the FDA has approved zoliflodacin (Nuzolvence) and gepotidacin (Blujepa) for patients aged ≥12 years.

The approvals provide additional oral treatment options at a time of increasing gonococcal antimicrobial resistance. Gepotidacin use is currently restricted to patients with few or no alternative treatment options because of limited safety data. 🦠💊

Explore the BMJ Best Practice Urethritis topic here: https://bestpractice.bmj.com/topics/en-gb/54

Clinical decision support wherever you are.Your free BMJ Best Practice trial includes:• Full app access• Offline functio...
30/05/2026

Clinical decision support wherever you are.

Your free BMJ Best Practice trial includes:
• Full app access
• Offline functionality
• 250+ calculators
• Procedural videos

https://bit.ly/43tP5WS

👃 “It’s just sinusitis” — until symptoms have lasted 12+ weeks.Chronic rhinosinusitis is more than a blocked nose:🔹 Faci...
29/05/2026

👃 “It’s just sinusitis” — until symptoms have lasted 12+ weeks.

Chronic rhinosinusitis is more than a blocked nose:
🔹 Facial pressure
🔹 Postnasal drip
🔹 Congestion
🔹 General malaise

Perhaps surprisingly, quality of life scores can be worse than those of some other chronic conditions such as heart failure and asthma.

Chronic rhinosinusitis can be classified into two groups, with and without polyps, which have slightly different treatment regimens. Our Best Practice topics on nasal polyps and chronic rhinosinusitis without nasal polyps have both recently been updated. Tap the links https://bit.ly/3Rw8G4L and https://bit.ly/4wYpEZR to refresh your knowledge on both scenarios and the treatments for each group.

PODCAST 🎧Bipolar disorder is common and important. So it is vital that we get the diagnosis and management of this condi...
28/05/2026

PODCAST 🎧
Bipolar disorder is common and important. So it is vital that we get the diagnosis and management of this condition right.

Learn more with Adrian Preda, Professor of Clinical Psychiatry at the University of California, Irvine.

https://bit.ly/4nFqRAI

🚨 Heat stroke is not the same as heat exhaustion or dehydration. It’s a medical emergency.As temperatures rise, keep you...
27/05/2026

🚨 Heat stroke is not the same as heat exhaustion or dehydration. It’s a medical emergency.

As temperatures rise, keep your radar up for:
🧠 Altered mental state — confusion, agitation, delirium, ataxia
🌡️ Core temp >40°C
💓 Tachycardia + hypotension
🧪 Early organ dysfunction: jaundice, coagulopathy, rhabdomyolysis

High-risk groups aren’t just elderly patients:
⚠️ Drug use e.g., anticholinergics, diuretics, phenothiazines, tricyclic antidepressants
⚠️ Alcohol & stimulant use
⚠️ Athletes and people exercising intensely in hot, humid conditions
⚠️ Patients unable to care for themselves or access fluids appropriately

Key management priorities:
❄️ Rapid cooling + removal from heat source
💧 Fluid resuscitation with isotonic fluids
🩸 Monitor for rhabdo/DIC
⏱️ Time-to-cooling matters

🔗 Click
https://bit.ly/49SNYCg to read more on this hot topic.

Not the kids (who would suggest such a thing!)..We’re talking about ticks! 🕷️⚠️Or more precisely, the spiral-shaped bact...
25/05/2026

Not the kids (who would suggest such a thing!)..We’re talking about ticks! 🕷️⚠️Or more precisely, the spiral-shaped bacteria of genus Borrelia, which is transmitted to humans by ticks and can cause the infection called Lyme disease. The most common initial manifestation is a typical skin lesion known as erythema migrans. Later manifestations may include arthritis, or central nervous system or cardiac involvement.

Ticks like to hang out in woodlands, heathland and long grass, sometimes even in urban parks and gardens, so be tick-aware if you are heading out for a picnic or festival this bank holiday and remember to check children and pets carefully. 👀🔍👆And head over to https://bit.ly/3RmXN5a for up to date information on Lyme disease and loads of useful images of the characteristic signs (including the mites themselves, in case you can’t tell one little critter from another..)

When your COPD patient has diabetes, how do you manage it?Try our free topic on Acute Exacerbation of COPD to see how th...
23/05/2026

When your COPD patient has diabetes, how do you manage it?

Try our free topic on Acute Exacerbation of COPD to see how the comorbidities manager helps you safely and effectively manage patients with comorbidities 🔽

https://bit.ly/4ozlYZ3

A 7-year-old boy has a chest x-ray for respiratory complaints and is incidentally found to have a prominent main pulmona...
22/05/2026

A 7-year-old boy has a chest x-ray for respiratory complaints and is incidentally found to have a prominent main pulmonary artery and cardiomegaly. On examination he has webbing of neck, short stature, and pectus carinatum. He has a systolic ejection murmur which is loudest over the left upper sternal border. Molecular genetic testing is positive for a gene mutation associated with Noonan syndrome.
? Find out at 🔗: https://bit.ly/49N5K9W

Important Update 📢WHO declares DRC and Uganda outbreak a global public health emergency. The World Health Organization (...
21/05/2026

Important Update 📢

WHO declares DRC and Uganda outbreak a global public health emergency.

The World Health Organization (WHO) has declared the Ebola outbreak in the Democratic Republic of the Congo (DRC) and Uganda a public health emergency of international concern (PHEIC). PHEIC status aims to accelerate funding, research, and international public health measures and co-operation to contain a disease.

https://bit.ly/4dp29Bt

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