19/06/2026
For individuals managing frequent headaches or migraines, acute pain relief is an essential resource. However, using these medications too often can inadvertently lock the brain into a chronic daily cycle.
Medication Overuse Headache (MOH) occurs when analgesics or triptans are taken regularly over several months. This constant exposure desensitizes the brain's natural pain-suppression pathways, causing a rebound headache to manifest as the medication clears the bloodstream. Because patients often mistake this withdrawal flare for a new headache and redose, they become trapped in a continuous loop.
Successful management requires patient education, structured withdrawal, and transitioning to evidence-based preventative strategies.
Access the complete diagnostic criteria and clinical management pathways on BMJ Best Practice here:
👉 https://bestpractice.bmj.com/topics/en-gb/3000344