08/24/2026
The 2026 theme, “25 Years On. Still Needed.,” reminds us that overdose awareness, prevention, compassionate support, and lifesaving action remain urgently important.
During an opioid overdose, breathing may become dangerously slow or stop completely. Without adequate breathing, the brain doesn't get the oxygen it needs to function.
🧠 Hypoxic brain injury occurs when the brain receives too little oxygen.
🧠 Anoxic brain injury occurs when the brain receives no oxygen.
Because brain cells are extremely sensitive to oxygen loss, injury can begin within minutes. A person who survives an overdose may experience changes in memory, movement, speech, vision, behavior, emotions, or independence. The effects can be temporary or lifelong.
An overdose-related brain injury is a brain injury. Survivors and their families deserve knowledgeable care, rehabilitation, resources, dignity, and support—without stigma.
If you suspect an opioid overdose, call 911 immediately, administer naloxone if available, follow the dispatcher’s instructions, and do not leave the person alone. Timely action can save both a life and a brain.
Today, we remember those who have died, support those who are living with the effects of overdose, and renew our commitment to prevention.