05/25/2026
Lichen Sclerosus and Vaginal Rejuvenation Therapy (CO2 Laser/Mona Lisa)
What is lichen sclerosus?
Lichen Sclerosus is a chronic, inflammatory disorder of the skin that most commonly affects post-menopausal women, and is mostly seen on the female anogenital epithelium. Sometimes lichen sclerosus can go unrecognized or misdiagnosed for several years, but over time it can lead to scarring, sexual dysfunction, and malignancy.
What is the treatment for lichen sclerosus?
The standard treatment for lichen sclerosus has included a 3-month application of potent topical corticosteroids, which have been shown to prevent malignant transformation. Recent studies have shown CO2 laser therapy results in symptom resolution, return to normal skin texture and color, and reduced risk of vulvar cancer. Based on a systematic review from 2023, combo therapy for lichen sclerosus with topical steroids and laser therapy results in greater reduction in itching/pain/dyspareunia and significantly higher patient satisfaction.