New Hope Molecular

03/08/2026

New publication by Dr. Pan

The understanding of suicidal ideation would be significantly enhanced by a biologically based measure that can meaningfully inform about the nature of the underlying neurocognitive alteration, as well as objectively identify individuals experiencing suicidal thoughts. Here we report on such an appr...

08/13/2025

This was an important collaboration for NHM.

An oligodendrocyte-specific genomic silencer element determines the cell type specificity for a fatal neurological disorder caused by a widely expressed nuclear protein (Lamin B1) and suggests a role for silencer elements in disease causation.

12/19/2023

12/16/2023

A new publication from New Hope Molecular. This paper was designed to discover blood biomarkers of suicidal ideation in treatment-refractory depression. The biomarkers we found put mitochondrial dysfunction in the spotlight. Plasma metabolomics also revealed personalized abnormalities in folate, carnitine, citrulline, and CoQ10.

Peripheral blood metabolomics was used to gain chemical insight into the biology of treatment-refractory Major Depressive Disorder with suicidal ideation, and to identify individualized differences for personalized care. The study cohort consisted of 99 patients with treatment-refractory major depre...

10/15/2023

New Hope Molecular provides consultation for severe treatment-refractory depression and suicidal ideation. Recently, Lisa Pan, MD presented the work behind New Hope Molecular at the International Academy of Su***de Research and the American Foundation for Su***de Prevention meeting.

New Hope Molecular 750 Washington Rd., Suite 19 Pittsburgh, PA 15228 412-682-9300

10/15/2023

Lisa Pan, MD is presenting the work behind New Hope Molecular this week at the International Association for Su***de Research and the American Foundation for Su***de Prevention meeting this week.

Providing consultation for treatment-refractory depression and suicidal behavior.

08/17/2023

05/21/2023

It’s been a busy year for New Hope Molecular. Our work was presented at the Wellcome MCPsych meeting at University of Oxford, accepted at the American College of Medical Genetics, looking forward to new collaborations to understand more about treatment-refractory depression and our work to prevent su***de.

11/04/2022

New publication from New Hope Molecular.

Metabolomic disorders: confirmed presence of potentially treatable abnormalities in patients with treatment refractory depression and suicidal behavior

10/11/2022

The 988 Su***de & Crisis Lifeline provides emotional support for people in distress in the U.S. 24/7 via text, call, and chat services. No judgment, just help 💜 Learn more at 988lifeline.org.

This page is not monitored 24/7.